Source: CLINVAR

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3 		fibroblast growth factor receptor 3 0.391 0.846 1.6E-05
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		disease 0.700 None 0.971 1 2 1997 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		B-Raf proto-oncogene, serine/threonine kinase 0.319 0.846 1.00
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		disease 0.500 None 0.944 1 11 2003 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		KRAS proto-oncogene, GTPase 0.320 0.923 7.9E-04
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		disease 0.500 None 1.000 1 5 2001 2019
Entrez Id: 4893
Gene Symbol: NRAS
NRAS 		NRAS proto-oncogene, GTPase 0.390 0.808 0.49
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		disease 0.500 None 1.000 1 6 1992 2019
Entrez Id: 3981
Gene Symbol: LIG4
LIG4 		DNA ligase 4 0.478 0.846 4.2E-06
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		disease 0.410 None 1.000 0 1 2002 2002
Entrez Id: 7157
Gene Symbol: TP53
TP53 		tumor protein p53 0.236 0.962 0.53
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		disease 0.200 None 1.000 1 26 1992 2020
Entrez Id: 567
Gene Symbol: B2M
B2M 		beta-2-microglobulin 0.447 0.846 0.56
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		disease 0.200 None 1.000 1 3 1988 2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha 0.292 0.923 1.00
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		disease 0.200 None 0.976 1 3 2002 2020
Entrez Id: 8085
Gene Symbol: KMT2D
KMT2D 		lysine methyltransferase 2D 0.465 0.808 1.00
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		disease 0.180 None 1.000 0 1 1989 2020
Entrez Id: 1019
Gene Symbol: CDK4
CDK4 		cyclin dependent kinase 4 0.412 0.808 6.3E-02
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		disease 0.150 None 1.000 1 2 2007 2019
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		HRas proto-oncogene, GTPase 0.378 0.885 8.0E-02
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		disease 0.130 None 1.000 1 8 1990 2016
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		isocitrate dehydrogenase (NADP(+)) 2 0.434 0.808 0.88
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		disease 0.120 None 1.000 1 2 2016 2019
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11 		protein tyrosine phosphatase non-receptor type 11 0.385 0.923 1.00
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		disease 0.120 None 1.000 1 3 2016 2019
Entrez Id: 3417
Gene Symbol: IDH1
IDH1 		isocitrate dehydrogenase (NADP(+)) 1 0.424 0.808 2.6E-12
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		disease 0.110 None 1.000 1 2 2016 2018
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2 		checkpoint kinase 2 0.460 0.808 1.2E-24
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		disease 0.100 None 0 1