Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3690
Gene Symbol: ITGB3
ITGB3
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		0.370 Biomarker CTD_human We report a significant main effect of the HTR5A gene in autism (P = 0.0088), and a significant three-locus model comprising a synergistic interaction between the ITGB3 and SLC6A4 genes with an additive effect of HTR5A (P < 0.0010). 17203304

2007
Entrez Id: 3690
Gene Symbol: ITGB3
ITGB3
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		0.370 Biomarker CTD_human Lastly, we show that a coding variant of ITGB3 is associated with autism susceptibility in a large multiplex sample (P = 0.00082), and that this variation has different effects in males and females (P = 0.0018). 16724005

2006
Entrez Id: 3690
Gene Symbol: ITGB3
ITGB3
CUI: C0004352
Disease: Autistic Disorder
Autistic Disorder 		0.370 Biomarker CTD_human We also show preliminary evidence that genotypes at the ITGB3 and SLC6A4 loci may interact to affect autism susceptibility (P=0.033). 16721604

2006