Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
CUI: C0008370
Disease: Cholestasis
Cholestasis 		0.300 Biomarker CTD_human Mechanisms of TNFalpha-induced cardiac dysfunction in cholestatic bile duct-ligated mice: interaction between TNFalpha and endocannabinoids. 20626112

2010
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
CUI: C0008370
Disease: Cholestasis
Cholestasis 		0.300 Biomarker CTD_human Our findings show that proinflammatory cytokines stimulate the biliary epithelium to generate NO, via NOS2 induction, and that NO causes ductular cholestasis by a RNOS-mediated inhibition of AC and of cAMP-dependent HCO(3)(-) and Cl(-) secretory mechanisms. 12612912

2003