Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3358
Gene Symbol: HTR2C
HTR2C
CUI: C0028754
Disease: Obesity
Obesity 		0.400 Biomarker CTD_human The frequency of patients homozygous for the HTR2C haplotype A (-759C, -697G, and 23Cys) was significantly higher among clozapine-treated patients with obesity (BMI >/= 30 kg/m) compared with nonobese patients (P = 0.015; odds ratio, 28; 95% confidence interval, 2-380). 19142110

2009
Entrez Id: 3358
Gene Symbol: HTR2C
HTR2C
CUI: C0028754
Disease: Obesity
Obesity 		0.400 Biomarker CTD_human Evidence was based on the observation that knock-out mice for the HTR2C receptor gene develop obesity and that many antipsychotics (AP) with potent HTR2C antagonism may induce weight gain in susceptible individuals. 17702092

2007