Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5621
Gene Symbol: PRNP
PRNP
CUI: C0162534
Disease: Prion Diseases
Prion Diseases 		0.500 Biomarker CTD_human Prion diseases are caused by the misfolding and aggregation of the prion protein (PrP). 17257012

2007
Entrez Id: 5621
Gene Symbol: PRNP
PRNP
CUI: C0162534
Disease: Prion Diseases
Prion Diseases 		0.500 Biomarker CTD_human Physiopathologic implications of the structural and functional domains of the prion protein. 17274528

2007
Entrez Id: 5621
Gene Symbol: PRNP
PRNP
CUI: C0162534
Disease: Prion Diseases
Prion Diseases 		0.500 Biomarker CTD_human Conversion of the normal membrane-bound prion protein (PrP-sen) to its pathological isoform (PrP-res) is a key event in the pathogenesis of transmissible spongiform encephalopathies. 11994310

2002
Entrez Id: 5621
Gene Symbol: PRNP
PRNP
CUI: C0162534
Disease: Prion Diseases
Prion Diseases 		0.500 Biomarker CTD_human However, the interplay between PrPs (PrP(C), PrP(Sc) and possibly other abnormal species), copper, anti-oxidation activity and pathogenesis of prion diseases remain unclear. 11701772

2001