Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0264956
Disease: Atheroma
Atheroma 		0.300 Biomarker CTD_human Kuwanon G attenuates atherosclerosis by upregulation of LXRα-ABCA1/ABCG1 and inhibition of NFκB activity in macrophages. 29355567

2018
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0264956
Disease: Atheroma
Atheroma 		0.300 Biomarker CTD_human Perinatal Bisphenol A Exposure Increases Atherosclerosis in Adult Male PXR-Humanized Mice. 29425287

2018
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0264956
Disease: Atheroma
Atheroma 		0.300 Biomarker CTD_human Effects of Icariin on Atherosclerosis and Predicted Function Regulatory Network in ApoE Deficient Mice. 30533443

2018
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0264956
Disease: Atheroma
Atheroma 		0.300 Biomarker CTD_human Using the Apolipoprotein E Knock-Out Mouse Model to Define Atherosclerotic Plaque Changes Induced by Low Dose Arsenic. 30376133

2018
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0264956
Disease: Atheroma
Atheroma 		0.300 Biomarker CTD_human Notoginsenoside R1 attenuates atherosclerotic lesions in ApoE deficient mouse model. 24933211

2014
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0264956
Disease: Atheroma
Atheroma 		0.300 Biomarker CTD_human Diesel exhaust particulate increases the size and complexity of lesions in atherosclerotic mice. 24330719

2013
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0264956
Disease: Atheroma
Atheroma 		0.300 Biomarker CTD_human Dyslipidemic apolipoprotein E-deficient mice chronically treated with intraperitoneal quercetin injections had smaller atheromatous lesions, reduced lipid deposition, and less macrophage and T cell inflammatory infiltrate in the aortic roots than vehicle-treated animals. 22869926

2012
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0264956
Disease: Atheroma
Atheroma 		0.300 Biomarker CTD_human Copper chelation by tetrathiomolybdate inhibits vascular inflammation and atherosclerotic lesion development in apolipoprotein E-deficient mice. 22770994

2012
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0264956
Disease: Atheroma
Atheroma 		0.300 Biomarker CTD_human Effects of paricalcitol and enalapril on atherosclerotic injury in mouse aortas. 20720404

2010
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0264956
Disease: Atheroma
Atheroma 		0.300 Biomarker CTD_human Thieno[2,3-c]isoquinolin-5-one, a potent poly(ADP-ribose) polymerase inhibitor, promotes atherosclerotic plaque regression in high-fat diet-fed apolipoprotein E-deficient mice: effects on inflammatory markers and lipid content. 19124646

2009
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0264956
Disease: Atheroma
Atheroma 		0.300 Biomarker CTD_human Poly(ADP-ribose) polymerase inhibition reduces atherosclerotic plaque size and promotes factors of plaque stability in apolipoprotein E-deficient mice: effects on macrophage recruitment, nuclear factor-kappaB nuclear translocation, and foam cell death. 17438151

2007