×
Entrez Id:
1717
Gene Symbol:
DHCR7
DHCR7
Smith-Lemli-Opitz Syndrome, Type I
0.300
Biomarker
CTD_human
Dichlorophenyl piperazines, including a recently-approved atypical antipsychotic, are potent inhibitors of DHCR7, the last enzyme in cholesterol biosynthesis.
29698737
2018
×
Entrez Id:
1717
Gene Symbol:
DHCR7
DHCR7
Smith-Lemli-Opitz Syndrome, Type I
0.300
Biomarker
CTD_human
Inhibitors of 7-Dehydrocholesterol Reductase: Screening of a Collection of Pharmacologically Active Compounds in Neuro2a Cells.
27097157
2016
×
Entrez Id:
1717
Gene Symbol:
DHCR7
DHCR7
Smith-Lemli-Opitz Syndrome, Type I
0.300
Biomarker
CTD_human
A patient with Smith-Lemli-Opitz syndrome: novel mutation of the DHCR7 gene and effects of therapy with simvastatin and cholesterol supplement.
19365639
2010
×
Entrez Id:
1717
Gene Symbol:
DHCR7
DHCR7
Smith-Lemli-Opitz Syndrome, Type I
0.300
Biomarker
CTD_human
Molecular screening of Smith-Lemli-Opitz syndrome in pregnant women from the Czech Republic.
17994283
2007
×
Entrez Id:
1717
Gene Symbol:
DHCR7
DHCR7
Smith-Lemli-Opitz Syndrome, Type I
0.300
Biomarker
CTD_human
Development and characterization of a hypomorphic Smith-Lemli-Opitz syndrome mouse model and efficacy of simvastatin therapy.
16446309
2006
×
Entrez Id:
1717
Gene Symbol:
DHCR7
DHCR7
Smith-Lemli-Opitz Syndrome, Type I
0.300
Biomarker
CTD_human
Ultraviolet A sensitivity in Smith-Lemli-Opitz syndrome: Possible involvement of cholesta-5,7,9(11)-trien-3 beta-ol.
16814115
2006
×
Entrez Id:
1717
Gene Symbol:
DHCR7
DHCR7
Smith-Lemli-Opitz Syndrome, Type I
0.300
Biomarker
CTD_human
Residual cholesterol synthesis and simvastatin induction of cholesterol synthesis in Smith-Lemli-Opitz syndrome fibroblasts.
15896653
2005
×
Entrez Id:
1717
Gene Symbol:
DHCR7
DHCR7
Smith-Lemli-Opitz Syndrome, Type I
0.300
Biomarker
CTD_human
Abnormal serotonergic development in a mouse model for the Smith-Lemli-Opitz syndrome: implications for autism.
14659996
2003
×
Entrez Id:
1717
Gene Symbol:
DHCR7
DHCR7
Smith-Lemli-Opitz Syndrome, Type I
0.300
Biomarker
CTD_human
27-Hydroxylation of 7- and 8-dehydrocholesterol in Smith-Lemli-Opitz syndrome: a novel metabolic pathway.
12906934
2003
×
Entrez Id:
1717
Gene Symbol:
DHCR7
DHCR7
Smith-Lemli-Opitz Syndrome, Type I
0.300
Biomarker
CTD_human
[Clinical characteristics and diagnosis of Smith-Lemli-Opitz syndrome and tentative phenotype-genotype correlation: report of 45 cases].
12818773
2003
×
Entrez Id:
1717
Gene Symbol:
DHCR7
DHCR7
Smith-Lemli-Opitz Syndrome, Type I
0.300
Biomarker
CTD_human
Oxysterols in the circulation of patients with the Smith-Lemli-Opitz syndrome: abnormal levels of 24S- and 27-hydroxycholesterol.
11254748
2001