Source: CTD_human

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma
0.600 Biomarker CTD_human Effects of curcumin and its adjuvant on TPC1 thyroid cell line. 30935902

2019

Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma
0.600 Biomarker CTD_human A Toxicogenomic Approach Reveals a Novel Gene Regulatory Network Active in In Vitro and In Vivo Models of Thyroid Carcinogenesis. 30621213

2019

Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma
0.600 Biomarker CTD_human A robust synergistic effect on thyroid gene expression and RAI uptake was observed in BRAF V600E-positive thyroid cancer cells when the two inhibitors were simultaneously used. 26751190

2016

Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma
0.600 Biomarker CTD_human Thus, this study has confirmed that the BRAF(T1799A) mutation confers cancer cells sensitivity to PLX4032 and demonstrated its specific potential as an effective and BRAF(T1799A) mutation-selective therapeutic agent for thyroid cancer. 21185263

2011

Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma
0.600 Biomarker CTD_human Suppression of BRAF pathway in thyroid cancer cell lines (8505C, TPC1 and C643) was achieved using RNA interference (RNAi) for BRAF and the kinase inhibitor, sorafenib. 19878585

2009

Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma
0.600 Biomarker CTD_human Clinical evaluation of B-RAF-targeting drugs is undergoing and trials in thyroid cancer are planned. 16940797

2006