DisGeNET - a database of gene-disease associations

Source: LHGDN

Disease: Bipolar Disorder ×

Gene: SLC6A4 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	6532
Gene Symbol:	SLC6A4

SLC6A4

CUI:	C0005586
Disease:	Bipolar Disorder

Bipolar Disorder

0.600

GeneticVariation

LHGDN

Is the 5-HTTLPR polymorphism associated with bipolar disorder or with suicidal behavior of bipolar disorder patients?

17579356

2008

Entrez Id:	6532
Gene Symbol:	SLC6A4

SLC6A4

CUI:	C0005586
Disease:	Bipolar Disorder

Bipolar Disorder

0.600

GeneticVariation

LHGDN

Serotonin transporter gene-linked polymorphic region: possible pharmacogenetic implications of rare variants.

16829782

2006

Entrez Id:	6532
Gene Symbol:	SLC6A4

SLC6A4

CUI:	C0005586
Disease:	Bipolar Disorder

Bipolar Disorder

0.600

Biomarker

LHGDN

The serotonin transporter (5-HTT) is a candidate gene for bipolar disorder (BPD).

15824745

2005

Entrez Id:	6532
Gene Symbol:	SLC6A4

SLC6A4

CUI:	C0005586
Disease:	Bipolar Disorder

Bipolar Disorder

0.600

GeneticVariation

LHGDN

Further evidence for a possible association between serotonin transporter gene and lithium prophylaxis in mood disorders.

15111989

2004