Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.200 PosttranslationalModification LHGDN Association of interindividual differences in p14ARF promoter methylation with single nucleotide polymorphism in primary colorectal cancer. 18327804

2008
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.200 PosttranslationalModification LHGDN Methylation of the MGMT and p16 genes in sporadic colorectal carcinoma and corresponding normal colonic mucosa. 18830187

2008
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.200 AlteredExpression LHGDN Inhibition of cell-cycle progression in human colorectal carcinoma Lovo cells by andrographolide. 18619950

2008
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.200 PosttranslationalModification LHGDN p16INK4a gene promoter hypermethylation in mucosa as a prognostic factor for patients with colorectal cancer. 18418463

2008
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.200 PosttranslationalModification LHGDN P16 methylation in serum as a potential marker for the malignancy of colorectal carcinoma. 17970082

2007
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.200 GeneticVariation LHGDN Stool-based DNA testing, a new noninvasive method for colorectal cancer screening, the first report from Iran. 17461444

2007
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.200 AlteredExpression LHGDN Cell-cycle and apoptosis regulators (p16INK4A, p21CIP1, beta-catenin, survivin, and hTERT) and morphometry-defined MPECs predict metachronous cancer development in colorectal adenoma patients. 17641414

2007
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.200 GeneticVariation LHGDN Molecular detection of TP53, Ki-Ras and p16INK4A promoter methylation in plasma of patients with colorectal cancer and its association with prognosis. Results of a 3-year GOIM (Gruppo Oncologico dell'Italia Meridionale) prospective study. 16760301

2006
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.200 AlteredExpression LHGDN Aberrant cytological localization of p16 and CDK4 in colorectal epithelia in the normal adenoma carcinoma sequence. 17072968

2006
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.200 PosttranslationalModification LHGDN Prognostic value of p16INK4a and p14ARF gene hypermethylation in human colon cancer. 16675157

2006
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.200 PosttranslationalModification LHGDN Methylation and expression of p16INK4 tumor suppressor gene in primary colorectal cancer tissues. 15809712

2005
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.200 AlteredExpression LHGDN Immunohistochemical analysis of thymidylate synthase, p16(INK4a), cyclin-dependent kinase 4 and cyclin D1 in colorectal cancers receiving preoperative chemotherapy: significance of p16(INK4a)-mediated cellular arrest as an indicator of chemosensitivity to 5-fluorouracil. 15260847

2004
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.200 PosttranslationalModification LHGDN Hypermethylation of the CDKN2A gene in colorectal cancer is associated with shorter survival. 12792748

2004
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.200 PosttranslationalModification LHGDN Differential impact of p16 inactivation by promoter methylation in non-small cell lung and colorectal cancer: clinical implications. 14719111

2004
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.200 PosttranslationalModification LHGDN Differences in loss of p16INK4 protein expression by promoter methylation between left- and right-sided primary colorectal carcinomas. 12963980

2003
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.200 AlteredExpression LHGDN Heterogeneous expression and association of beta-catenin, p16 and c-myc in multistage colorectal tumorigenesis and progression detected by tissue microarray. 14601048

2003