Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0013295
Disease: Duodenal Ulcer
Duodenal Ulcer
0.090 GeneticVariation LHGDN Association of specific haplotype of TNFalpha with Helicobacter pylori-mediated duodenal ulcer in eastern Indian population. 19147919

2008

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0013295
Disease: Duodenal Ulcer
Duodenal Ulcer
0.090 GeneticVariation LHGDN In conclusion, among host genetic factors contributing to H. pylori disease outcome, IFN-G +874 AA genotype favors cagA positive infections, TNF-A -857 TT duodenal ulcer while IL-10 -819 TT intestinal metaplasia and NCGC. 15652446

2005

Entrez Id: 7124
Gene Symbol: TNF
TNF
CUI: C0013295
Disease: Duodenal Ulcer
Duodenal Ulcer
0.090 GeneticVariation LHGDN However, the frequencies of individual haplotypes C and D, which had opposite alleles at -1031, -863, and -857, showed statistically significant differences between the gastric cancer and duodenal ulcer (P=0.005 and P=0.02, respectively), suggesting that the TNF/LTA genotypes might play an opposite role in the pathogenesis of gastric cancer and duodenal ulcer. 15381184

2004