Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 GeneticVariation LHGDN KRAS, and CMET mutations are associated with advanced non-small cell lung cancer. 19096301

2009

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 Biomarker LHGDN both Kras and integrin alpha1beta1 cooperate to drive the growth of non-small cell lung cancer in vivo 18676835

2008

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 GeneticVariation LHGDN study of EGFR, HER2, TP53 & KRAS mutations of p14arf expression of non-small cell lung cancers in relation to smoking 17575133

2007

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 GeneticVariation LHGDN EGFR and K-ras mutations may have a role in progression of resected non-small-cell lung cancer 17596643

2007

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 AlteredExpression LHGDN Activated K-ras is associated with non-small cell lung cancer 17549340

2007

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 GeneticVariation LHGDN Kras mutant lung cancer patients have a significantly worse prognosis than wild-type patients. 17671710

2007

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 AlteredExpression LHGDN Rna silencing of K-ras (V12) markedly decreased K-ras (V12) gene expression and inhibited cellular proliferation of lung cancer cells. 17172815

2007

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 GeneticVariation LHGDN Circulating KRAS mutations originate from tumors and are prognostically relevant in lung cancer. 17449174

2007

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 GeneticVariation LHGDN Mutations in either the EGFR TK domain or the KRAS gene can lead to lung cancer pathogenesis/TK domain mutations are the first molecular change known to occur specifically in never smokers. 15741570

2005

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 GeneticVariation LHGDN findings indicate the wild-type KRAS allele is occasionally lost in lung cancer and the oncogenic activation of mutant KRAS is more frequently associated with overexpression of the mutant allele than with loss of the wild-type allele in NSCLC development 14601056

2004

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 GeneticVariation LHGDN codon 12 K-ras mutations in lung tumors or sputum samples from 102 lung cancer patients 12826308

2003

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 Biomarker LHGDN Detection of P21 may be used as the screening marker for diagnosis of polycyclic aromatic hydrocarbons (PAHs) -related lung cancer related lung cancer, and may supplement the diagnostic value of conventional cytology. 14761400

2003

Entrez Id: 3845
Gene Symbol: KRAS
KRAS
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.600 Biomarker LHGDN LOH of chromosome 12p was seen in about 50% of human lung adenocarcinomas & large cell carcinomas/mutations were seen at codon 12 in about 40% of adenocarcinomas & large cell carcinomas/wild-type Kras2 is a tumor suppressor of lung cancer. 12606951

2003