Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
CUI: C0025202
Disease: melanoma
melanoma 		0.100 AlteredExpression LHGDN Indirect immunofluorescence confirmed the presence of NF-kappaB p50 and p65 in melanoma cell nuclei, with p50 being more prevalent. 18668140

2009
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
CUI: C0025202
Disease: melanoma
melanoma 		0.100 Biomarker LHGDN Our results demonstrate for the first time that the NF-kappaB p50 subunit mediates melanoma angiogenesis by specifically upregulating IL-6, highlighting a novel and important role for the NF-kappaB p50/IL-6 signaling axis in melanoma progression. 18942706

2009
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
CUI: C0025202
Disease: melanoma
melanoma 		0.100 Biomarker LHGDN Diacylglycerol kinase alpha suppresses tumor necrosis factor-alpha-induced apoptosis of human melanoma cells through NF-kappaB activation. 17276726

2007
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
CUI: C0025202
Disease: melanoma
melanoma 		0.100 AlteredExpression LHGDN CCAAT displacement protein regulates nuclear factor-kappa beta-mediated chemokine transcription in melanoma cells. 17496784

2007
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
CUI: C0025202
Disease: melanoma
melanoma 		0.100 GeneticVariation LHGDN Importance of polymorphisms in NF-kappaB1 and NF-kappaBIalpha genes for melanoma risk, clinicopathological features and tumor progression in Swedish melanoma patients. 17492467

2007
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
CUI: C0025202
Disease: melanoma
melanoma 		0.100 Biomarker LHGDN In addition, overexpression of NF-kappaB p50 induced RhoA activity and Rock-mediated formation of stress fiber in melanoma cells. 16951147

2006
Entrez Id: 4790
Gene Symbol: NFKB1
NFKB1
CUI: C0025202
Disease: melanoma
melanoma 		0.100 AlteredExpression LHGDN Comparative expression of NFkappaB proteins in melanocytes of normal skin vs. benign intradermal naevus and human metastatic melanoma biopsies. 15016307

2004