DisGeNET - a database of gene-disease associations

Source: LHGDN

Disease: Multiple Myeloma ×

Gene: HSPB1 ×

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	3315
Gene Symbol:	HSPB1

HSPB1

CUI:	C0026764
Disease:	Multiple Myeloma

Multiple Myeloma

0.330

AlteredExpression

LHGDN

These data demonstrate that Hsp27 inhibits the release of Smac, and thereby confers Dex resistance in MM cells.

2003