Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.100 Biomarker LHGDN We found that ursolic acid, a pentacyclic triterpenoid, inhibited both constitutive and interleukin-6-inducible STAT3 activation in a dose- and time-dependent manner in multiple myeloma cells. 17855663

2007

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.100 AlteredExpression LHGDN Overall, our results indicate that fresh cells from MM patients express constitutively active NF-kappaB and STAT3, and suppression of these transcription factors inhibits the survival of the cells. 15070700

2004

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.100 AlteredExpression LHGDN Interleukin-6-dependent gene expression profiles in multiple myeloma INA-6 cells reveal a Bcl-2 family-independent survival pathway closely associated with Stat3 activation. 12969979

2004

Entrez Id: 6774
Gene Symbol: STAT3
STAT3
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.100 Biomarker LHGDN Consequently, mumps virus V protein prevents responses to interleukin-6 and v-Src signals and can induce apoptosis in STAT3-dependent multiple myeloma cells and transformed murine fibroblasts. 12743296

2003