Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7468
Gene Symbol: NSD2
NSD2
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.100 AlteredExpression LHGDN Collectively, these data suggest that, by acting directly as a modifier of chromatin as well as through binding of other chromatin-modifying enzymes, MMSET influences gene expression and potentially acts as a pathogenic agent in multiple myeloma. 18156491

2008
Entrez Id: 7468
Gene Symbol: NSD2
NSD2
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.100 GeneticVariation LHGDN Quantitative reverse-transcription-polymerase chain reaction (RT-PCR) for proposed target genes on a panel of myeloma cell lines and purified plasma cells showed that only transcripts originating from the WHSC1/MMSET/NSD2 gene are uniformly dysregulated in all t(4;14)POS patients. 15677557

2005
Entrez Id: 7468
Gene Symbol: NSD2
NSD2
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.100 AlteredExpression LHGDN A subset of multiple myeloma harboring the t(4;14)(p16;q32) translocation lacks FGFR3 expression but maintains an IGH/MMSET fusion transcript. 12433679

2003