Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 Biomarker LHGDN An N-terminal fragment of insulin-like growth factor binding protein-3 (IGFBP-3) induces apoptosis in human prostate cancer cells in an IGF-independent manner. 17959403

2008
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 Biomarker LHGDN IGFBP-3 sensitizes prostate cancer cells to interferon-gamma-induced apoptosis. 17719815

2008
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 GeneticVariation LHGDN Induction of apoptosis in human prostate cancer cells by insulin-like growth factor binding protein-3 does not require binding to retinoid X receptor-alpha. 18162523

2008
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 GeneticVariation LHGDN Grade-specific prostate cancer associations of IGF1 (CA)19 repeats and IGFBP3-202A/C in blacks and whites. 17668637

2007
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 PosttranslationalModification LHGDN In silico mining identifies IGFBP3 as a novel target of methylation in prostate cancer. 17453001

2007
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 Biomarker LHGDN Contribution of the orphan nuclear receptor Nur77 to the apoptotic action of IGFBP-3. 17434920

2007
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 AlteredExpression LHGDN Circulating insulin-like growth factor-I and binding protein-3 and risk of prostate cancer. 16775172

2006
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 AlteredExpression LHGDN Role of insulin-like growth factor binding proteins in 1alpha,25-dihydroxyvitamin D(3)-induced growth inhibition of human prostate cancer cells. 15651061

2005
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 AlteredExpression LHGDN cDNA microarray analysis with amplified RNA after isolation of intact cellular RNA from neoplastic and non-neoplastic prostate tissue separated by laser microdissections. 15067329

2004
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 Biomarker LHGDN Insulin-like growth factor binding protein-3 induces early apoptosis in malignant prostate cancer cells and inhibits tumor formation in vivo. 11948969

2002
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 Biomarker LHGDN Insulin-like growth factor-I (IGF-I) and IGF binding protein-3 as predictors of advanced-stage prostate cancer. 12122101

2002
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 GeneticVariation LHGDN Insulin-like growth factor (IGF)-binding protein-3 mutants that do not bind IGF-I or IGF-II stimulate apoptosis in human prostate cancer cells. 11784719

2002