Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms 		0.100 Biomarker LHGDN Marker chromosomes are a significant mechanism of high-level RUNX1 gene amplification in hematologic malignancies. 19167608

2009
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms 		0.100 GeneticVariation LHGDN Through the use of polymerase chain reaction-single-strand conformation polymorphism analysis, we examined the AML1 gene for mutations in 241 patients with pediatric hematologic malignancies, and we detected AML1 mutations in seven patients (2.9%). 12874780

2003
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms 		0.100 GeneticVariation LHGDN In this review, we summarize mutational changes of the AML1 gene in hematological malignancies, especially in MDS and discuss the mechanism whereby the mutant acts as a dominant negative inhibitor of wild-type AML1. 12002768

2002