DisGeNET - a database of gene-disease associations

Gene: TLR4 ×

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Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	7099
Gene Symbol:	TLR4

TLR4

CUI:	C0403447
Disease:	Chronic Kidney Insufficiency

Chronic Kidney Insufficiency

0.010

AlteredExpression

LHGDN

Reduced expression of Toll-like receptor 4 contributes to impaired cytokine response of monocytes in uremic patients.

2006