Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP
CUI: C0497327
Disease: Dementia
Dementia 		0.100 GeneticVariation LHGDN Intracellular accumulation of TDP-43 is observed in a subpopulation of patients with other dementia disorders, including Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). 19139911

2009
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP
CUI: C0497327
Disease: Dementia
Dementia 		0.100 Biomarker LHGDN Loss-of-function mutations in progranulin (GRN) cause ubiquitin- and TAR DNA-binding protein 43 (TDP-43)-positive frontotemporal dementia (FTLD-U), a progressive neurodegenerative disease affecting approximately 10% of early-onset dementia patients. 18723524

2008
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP
CUI: C0497327
Disease: Dementia
Dementia 		0.100 Biomarker LHGDN TDP-43 immunoreactivity in anoxic, ischemic and neoplastic lesions of the central nervous system. 18087705

2008
Entrez Id: 23435
Gene Symbol: TARDBP
TARDBP
CUI: C0497327
Disease: Dementia
Dementia 		0.100 Biomarker LHGDN TDP-43 pathology in familial frontotemporal dementia and motor neuron disease without Progranulin mutations. 17360763

2007