Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0497327
Disease: Dementia
Dementia 		0.500 Biomarker LHGDN In vivo and postmortem clinicoanatomical correlations in frontotemporal dementia and parkinsonism linked to chromosome 17. 18322394

2008
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0497327
Disease: Dementia
Dementia 		0.500 GeneticVariation LHGDN The extended tau haplotype and the age of onset of dementia in Down syndrome. 18765933

2008
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0497327
Disease: Dementia
Dementia 		0.500 GeneticVariation LHGDN The tau S305S mutation causes frontotemporal dementia with parkinsonism. 18093153

2008
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0497327
Disease: Dementia
Dementia 		0.500 Biomarker LHGDN CSF total and phosphorylated tau protein, regional glucose metabolism and dementia severity in Alzheimer's disease. 18803648

2008
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0497327
Disease: Dementia
Dementia 		0.500 GeneticVariation LHGDN Although rare, a tau-related dementia with mutations in the microtubule-associated protein tau gene (MAPT) has been identified in patients showing clinical presentations similar to those of AD. 18587238

2008
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0497327
Disease: Dementia
Dementia 		0.500 GeneticVariation LHGDN The novel Tau mutation G335S: clinical, neuropathological and molecular characterization. 17186252

2007
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0497327
Disease: Dementia
Dementia 		0.500 GeneticVariation LHGDN A novel MAPT mutation (P301T) associated with familial frontotemporal dementia. 17662000

2007
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0497327
Disease: Dementia
Dementia 		0.500 GeneticVariation LHGDN Hereditary frontotemporal dementia caused by Tau gene mutations. 17493040

2007
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0497327
Disease: Dementia
Dementia 		0.500 Biomarker LHGDN Heterogeneity of ubiquitin pathology in frontotemporal lobar degeneration: classification and relation to clinical phenotype. 17021754

2006
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0497327
Disease: Dementia
Dementia 		0.500 Biomarker LHGDN Characterization of tau pathologies in gray and white matter of Guam parkinsonism-dementia complex. 16609851

2006
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0497327
Disease: Dementia
Dementia 		0.500 Biomarker LHGDN Pathological changes in the microtubule associated protein tau are a major hallmark of many human dementias collectively defined as tauopathies. 15750210

2005
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0497327
Disease: Dementia
Dementia 		0.500 GeneticVariation LHGDN Familial frontotemporal dementia associated with the novel MAPT mutation T427M. 15940384

2005
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0497327
Disease: Dementia
Dementia 		0.500 GeneticVariation LHGDN Novel G335V mutation in the tau gene associated with early onset familial frontotemporal dementia. 15765246

2005
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0497327
Disease: Dementia
Dementia 		0.500 GeneticVariation LHGDN Phenotypic variation in frontotemporal dementia and parkinsonism linked to chromosome 17. 15178932

2004
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0497327
Disease: Dementia
Dementia 		0.500 Biomarker LHGDN The role of tau (MAPT) in frontotemporal dementia and related tauopathies. 15365985

2004
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0497327
Disease: Dementia
Dementia 		0.500 GeneticVariation LHGDN Frontotemporal dementia and parkinsonism with the P301S tau gene mutation in a Jewish family. 12796837

2003
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0497327
Disease: Dementia
Dementia 		0.500 GeneticVariation LHGDN Tau haplotype frequency in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. 12710929

2003
Entrez Id: 4137
Gene Symbol: MAPT
MAPT
CUI: C0497327
Disease: Dementia
Dementia 		0.500 Biomarker LHGDN Tau negative frontal lobe dementia at 17q21: significant finemapping of the candidate region to a 4.8 cM interval. 12476321

2002