Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.050 Biomarker LHGDN These data suggest that Raf-1 is the predominant Raf isoform responsible for regulating cellular growth in ovarian cancer cells and may be particularly important in high grade serous ovarian cancers. 16332724

2006
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.050 AlteredExpression LHGDN A panel of 15 ovarian cancer cell lines was used to model a range of growth responses to ASOs targeting Raf-1 mRNA. 15041731

2004
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.050 PosttranslationalModification LHGDN Our findings suggest that paclitaxel induces the phosphorylation of BAD Ser-112 via the ERK cascade, and the phosphorylation of both BAD Ser-136 and Raf-1 Ser-259 via the PI-3K-Akt cascade, and that inhibition of either of these cascades sensitizes ovarian cancer cells to paclitaxel. 12087097

2002