Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.060 AlteredExpression LHGDN Activation of p70S6K induces expression of matrix metalloproteinase 9 associated with hepatocyte growth factor-mediated invasion in human ovarian cancer cells. 16469801

2006
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.060 AlteredExpression LHGDN This study demonstrates a novel mechanism of EGF-induced VEGF and HIF-1alpha expression through production of H2O2 and activation of AKT and p70S6K1 in human ovarian cancer cells. 17045920

2006
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.060 AlteredExpression LHGDN G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells. 15028555

2004
Entrez Id: 6198
Gene Symbol: RPS6KB1
RPS6KB1
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.060 AlteredExpression LHGDN These results demonstrate that SU5416 inhibited VEGF and HIF-1alpha expression through the inhibition of PI3K/AKT/p70S6K1 pathway in ovarian cancer cells. 15474452

2004