Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6790
Gene Symbol: AURKA
AURKA
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.090 AlteredExpression LHGDN Overexpression of the centrosomal protein Aurora-A kinase is associated with poor prognosis in epithelial ovarian cancer patients. 17634535

2007
Entrez Id: 6790
Gene Symbol: AURKA
AURKA
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.090 AlteredExpression LHGDN Higher BTAK expression was found in ovarian cancer cells compared to ovaries without cancer but with known BRCA1/2 mutation or strong family history (P<0.001), and expression levels of BTAK and p53 were directly correlated (r=0.306; P<0.001). 17673924

2007
Entrez Id: 6790
Gene Symbol: AURKA
AURKA
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.090 AlteredExpression LHGDN Aurora-A induces cell survival and chemoresistance by activation of Akt through a p53-dependent manner in ovarian cancer cells. 16894566

2006
Entrez Id: 6790
Gene Symbol: AURKA
AURKA
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.090 AlteredExpression LHGDN STK15 mRNA was found overexpressed in 10 of the 15 ovarian cancer cell cultures. 15839305

2005
Entrez Id: 6790
Gene Symbol: AURKA
AURKA
CUI: C0919267
Disease: ovarian neoplasm
ovarian neoplasm 		0.090 Biomarker LHGDN To our knowledge, this is the first demonstration of recurrent activation and overexpression of BTAK/Aurora-A in human ovarian cancer, which may play a critical role in development of this malignancy. 12684414

2003