Source: LHGDN

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Heme oxygenase-1 inhibits breast cancer invasion via suppressing the expression of matrix metalloproteinase-9. 18483307

2008
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN In 560 human breast tumors, AIB1 expression was found to be positively associated with PEA3, MMP2, and MMP9. 18644862

2008
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Gene transfer of matrix metalloproteinase-9 induces tumor regression of breast cancer in vivo. 18451168

2008
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 Biomarker LHGDN Surgical excision promotes tumor growth and metastasis by promoting expression of MMP-9 and VEGF in a breast cancer model. 18438343

2008
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 GeneticVariation LHGDN Promoter polymorphisms in matrix metalloproteinases and their inhibitors: few associations with breast cancer susceptibility and progression. 17033924

2007
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 Biomarker LHGDN Up-regulation of CD147 and matrix metalloproteinase-2, -9 induced by P-glycoprotein substrates in multidrug resistant breast cancer cells. 17725804

2007
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Furthermore, targeting both uPAR and MMP-9 totally regressed orthotopic breast tumors in nude mice. 17657740

2007
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Circulating MMP2 and MMP9 in breast cancer -- potential role in classification of patients into low risk, high risk, benign disease and breast cancer categories. 16615109

2006
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN A splice variant of CD99 increases motility and MMP-9 expression of human breast cancer cells through the AKT-, ERK-, and JNK-dependent AP-1 activation signaling pathways. 16984917

2006
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 GeneticVariation LHGDN Polymorphisms of the promoter regions of matrix metalloproteinases genes MMP-1 and MMP-9 in breast cancer. 16267613

2006
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Expression of MMP2, MMP9 and MMP3 in breast cancer brain metastasis in a rat model. 16158251

2005
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN The matrix metalloproteinase-9/neutrophil gelatinase-associated lipocalin complex plays a role in breast tumor growth and is present in the urine of breast cancer patients. 16061852

2005
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 GeneticVariation LHGDN Genetic polymorphisms in the MMP-2 and MMP-9 genes and breast cancer phenotype. 15609121

2004
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer with a special reference to activator protein-2, HER2, and prognosis. 15569994

2004
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 Biomarker LHGDN Endometase/matrilysin-2 in human breast ductal carcinoma in situ and its inhibition by tissue inhibitors of metalloproteinases-2 and -4: a putative role in the initiation of breast cancer invasion. 14744773

2004
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Plasma MMP-9 (92 kDa-MMP) activity is useful in the follow-up and in the assessment of prognosis in breast cancer patients. 12866035

2003
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 Biomarker LHGDN [Expression of matrix metalloproteinase 9 (MMP-9) and laminin-receptor in breast carcinoma and their correlation with tumor metastasis and prognosis]. 12753719

2003
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 Biomarker LHGDN Activated integrin alphavbeta3 cooperates with metalloproteinase MMP-9 in regulating migration of metastatic breast cancer cells. 12874388

2003
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 Biomarker LHGDN Inhibition of fibroblast-mediated breast tumor cell invasion by an anti-TSP-1 or an anti-MMP-9 antibody was evaluated using a modified Boyden chamber. 12219015

2002
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.400 AlteredExpression LHGDN Multiple signaling pathways involved in activation of matrix metalloproteinase-9 (MMP-9) by heregulin-beta1 in human breast cancer cells. 11781819

2001