Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7166
Gene Symbol: TPH1
TPH1
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.360 Biomarker PSYGENET The TPH1 A218C polymorphism is a potential biomarker for bipolar disorder and alcohol dependence risk in Caucasian population. 21601290

2012
Entrez Id: 7166
Gene Symbol: TPH1
TPH1
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.360 Biomarker PSYGENET Further replication of these findings in additional large case-control and family-based association is needed before TPH can be designated a risk gene for bipolar disorder. 19032713

2008
Entrez Id: 7166
Gene Symbol: TPH1
TPH1
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.360 Biomarker PSYGENET With respect to TPH1 and TPH2, the majority of studies did not provide evidence for an association between these genes and bipolar disorder. 15727488

2005
Entrez Id: 7166
Gene Symbol: TPH1
TPH1
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.360 Biomarker PSYGENET Polymorphism screening and haplotype analysis of the tryptophan hydroxylase gene (TPH1) and association with bipolar affective disorder in Taiwan. 15799788

2005
Entrez Id: 7166
Gene Symbol: TPH1
TPH1
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder 		0.360 Biomarker PSYGENET Although the tryptophan hydroxylase isoform-1 gene (Tph1) has been reported to have a genetic association with bipolar disorder and schizophrenia, the Tph1 isoform is expressed at much lower levels than Tph2 (150-fold less in the mouse brain). 16240163

2005