Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 116
Gene Symbol: ADCYAP1
ADCYAP1
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.310 Biomarker PSYGENET We previously found that juvenile pituitary adenylate cyclase-activating polypeptide (PACAP)-knockout (PACAP(-/-)) mice reared in an enriched environment (EE) for 4 weeks showed attenuated hyperactivity, jumping behavior, impairments in social interaction, and depression-like behavior. 25014004

2014
Entrez Id: 116
Gene Symbol: ADCYAP1
ADCYAP1
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.310 Biomarker PSYGENET The behavioral phenotype of pituitary adenylate-cyclase activating polypeptide-deficient mice in anxiety and depression tests is accompanied by blunted c-Fos expression in the bed nucleus of the stria terminalis, central projecting Edinger-Westphal nucleus, ventral lateral septum, and dorsal raphe nucleus. 22178610

2012
Entrez Id: 116
Gene Symbol: ADCYAP1
ADCYAP1
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.310 Biomarker PSYGENET Adult PACAP(-/-) mice showed not only hyperactivity, jumping behavior, and depression-like behavior, but also decreased social interaction. 20144662

2010
Entrez Id: 116
Gene Symbol: ADCYAP1
ADCYAP1
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.310 Biomarker PSYGENET We recently reported depression-like behavior in the forced swimming test in PACAP deficient mice. 19914336

2010