Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7349
Gene Symbol: UCN
UCN
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.320 Biomarker PSYGENET In mice over-expressing neuronal CRF (an animal model for depression) the expression of urocortin 1 (Ucn1) in the non-preganglionic Edinger-Westphal nucleus (npEW) is strongly down-regulated. 18329817

2008
Entrez Id: 7349
Gene Symbol: UCN
UCN
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.320 Biomarker PSYGENET These data indicate that CRF receptor antagonists may be useful for the treatment of the disease states where CRF is elevated such as anxiety and depression, anorexia nervosa and stroke and that ligand inhibitors of CRF-BP may be used to elevate brain levels of 'free' urocortin and other CRF-related peptides. 9118350

1996