Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.400 Biomarker PSYGENET The significantly higher homocysteine levels observed in MDD patients compared to controls after adjustment for age and sex (p?=?0.030), therefore appears to be mediated by the effects of MTHFR 677 C > T and low folate intake on BMI. 24532086

2015

Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.400 Biomarker PSYGENET Our results suggest that the MTHFR C677T polymorphism may serve as a marker for MDD prognosis pending independent replication. 24123968

2014

Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.400 Biomarker PSYGENET Individuals with the genotype COMT Met/Val and MTHFR C/T have more probability of suffering from MDD. 24751310

2014

Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.400 Biomarker PSYGENET Our results show that the effects of TCEs on the prospectively assessed recurrence of MDD and self-reported depressive symptoms in the general population depend on the MTHFR genotype. 23900311

2013

Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder
0.400 Biomarker PSYGENET This study shows that CC genotype of the MTHFR A1298C is associated with higher risk of MDD in Slovak population. 23255668

2013