Source: PSYGENET

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6999
Gene Symbol: TDO2
TDO2
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.330 Biomarker PSYGENET Lack of association between TPH2 gene polymorphisms with major depressive disorder in multiethnic Malaysian population. 24376086

2015
Entrez Id: 6999
Gene Symbol: TDO2
TDO2
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.330 Biomarker PSYGENET Tryptophan hydroxylase 2 gene is associated with cognition in late-onset depression in a Chinese Han population. 26057341

2015
Entrez Id: 6999
Gene Symbol: TDO2
TDO2
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.330 Biomarker PSYGENET Stimulation of 5-HT2C receptors improves cognitive deficits induced by human tryptophan hydroxylase 2 loss of function mutation. 24196946

2014
Entrez Id: 6999
Gene Symbol: TDO2
TDO2
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.330 Biomarker PSYGENET Chronic SSRI treatment exacerbates serotonin deficiency in humanized Tph2 mutant mice. 23336047

2013
Entrez Id: 6999
Gene Symbol: TDO2
TDO2
CUI: C1269683
Disease: Major Depressive Disorder
Major Depressive Disorder 		0.330 Biomarker PSYGENET Cortical-amygdalar circuit dysfunction in a genetic mouse model of serotonin deficiency. 23467366

2013