×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
Genetic mutations of p53 and k-ras in gastric carcinoma patients from Hunan, China.
21080251 2011
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
CausalMutation
CLINVAR
Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: a prospective observational study.
21601526 2011
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
CausalMutation
CLINVAR
Pleomorphic carcinoma of the lung arising in a patient with Li-Fraumeni syndrome: report of a case.
21626334 2011
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
Prevalence of germline TP53 mutations in a prospective series of unselected patients with adrenocortical carcinoma.
23175693 2013
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
The genetic landscape of high-risk neuroblastoma.
23334666 2013
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
CausalMutation
CLINVAR
Joint effects of germ-line TP53 mutation, MDM2 SNP309, and gender on cancer risk in family studies of Li-Fraumeni syndrome.
21305319 2011
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
CausalMutation
CLINVAR
Molecular basis of the Li-Fraumeni syndrome: an update from the French LFS families.
18511570 2008
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
CausalMutation
CLINVAR
Germ-line p53 mutations in 15 families with Li-Fraumeni syndrome.
7887414 1995
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
CausalMutation
CLINVAR
Detection of high frequency of mutations in a breast and/or ovarian cancer cohort: implications of embracing a multi-gene panel in molecular diagnosis in India.
26911350 2016
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
Frequency of mutations in individuals with breast cancer referred for BRCA1 and BRCA2 testing using next-generation sequencing with a 25-gene panel.
25186627 2015
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
Malignant peritoneal mesothelioma in a patient with Li-Fraumeni syndrome.
21464421 2011
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
CausalMutation
CLINVAR
Two hot spot mutant p53 mouse models display differential gain of function in tumorigenesis.
23538418 2013
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
CausalMutation
CLINVAR
The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis.
23161690 2013
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
CausalMutation
CLINVAR
Gastric cancer in individuals with Li-Fraumeni syndrome.
21552135 2011
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
CausalMutation
CLINVAR
Occurrence of Neuroblastoma among TP53 p.R337H Carriers.
26452166 2015
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
BRCA1, TP53, and CHEK2 germline mutations in uterine serous carcinoma.
22811390 2013
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
CausalMutation
CLINVAR
TP53 germline mutation testing in 180 families suspected of Li-Fraumeni syndrome: mutation detection rate and relative frequency of cancers in different familial phenotypes.
20522432 2010
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
CausalMutation
CLINVAR
Early onset HER2-positive breast cancer is associated with germline TP53 mutations.
21761402 2012
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
CausalMutation
CLINVAR
Panel Testing for Familial Breast Cancer: Calibrating the Tension Between Research and Clinical Care.
26786923 2016
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
CausalMutation
CLINVAR
Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes.
21343334 2011
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
Clinical Application of Multigene Panels: Challenges of Next-Generation Counseling and Cancer Risk Management.
26484312 2015
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
CausalMutation
CLINVAR
R337H mutation of the TP53 gene as a clinical marker in cancer patients: a systematic review of literature.
26681051 2015
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
Frequent germline deleterious mutations in DNA repair genes in familial prostate cancer cases are associated with advanced disease.
24556621 2014
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
CausalMutation
CLINVAR
Analysis of the DNA-binding activity of p53 mutants using functional protein microarrays and its relationship to transcriptional activation.
20128691 2010
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
LI-FRAUMENI SYNDROME 1
0.100
GeneticVariation
CLINVAR
TP53 germline mutation testing in 180 families suspected of Li-Fraumeni syndrome: mutation detection rate and relative frequency of cancers in different familial phenotypes.
20522432 2010