×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
ACTH hypertension in the rat: role of sodium chloride.
1321011
1992
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Changes in pressor responsiveness do not explain ACTH hypertension .
3015460
1986
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Haemodynamic mechanisms of corticotropin (ACTH)-induced hypertension in the rat.
10658937
1999
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Nitric oxide synthase activity in adrenocorticotrophin-induced hypertension in the rat.
11703388
2001
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
The role of this increased pressor responsiveness in ACTH /steroid-induced hypertension remains to be determined.
1321309
1992
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Adrenocorticotrophin-induced hypertension in rats. Role of progesterone and digoxin-like substances.
8136112
1994
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
However, when RAP is not allowed to rise, ACTH is associated with sodium retention and severe systemic hypertension , suggesting that the natriuretic effects of ACTH are caused by increased RAP and that the natriuresis blunts the chronic hypertensive effects of ACTH .
2849322
1988
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Antioxidant vitamins and adrenocorticotrophic hormone-induced hypertension in rats.
17994356
2007
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
L-arginine partially reverses established adrenocorticotrophin-induced hypertension and nitric oxide deficiency in the rat.
11193135
2000
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
This result indicates that the cardiac glycoside binding site of the alpha1 isoform can also mediate ACTH -induced hypertension .
16243970
2005
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Effects of bromocriptine on blood pressure and plasma beta-endorphin in spontaneously hypertensive rats.
6274577
1981
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Vasodilator prostanoids and ACTH -dependent hypertension .
6135010
1983
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Thus, NAC partially prevented but did not reverse ACTH -induced hypertension .
16546835
2006
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Exaggerated natriuresis in ACTH hypertension in sheep.
216942
1978
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Influence of somatostatin analogue (SMS 201-995, octreotide) on blood pressure in adrenocorticotrophin (ACTH) treated rats: role of hyperinsulinaemia in ACTH hypertension.
8261660
1993
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Effect of sodium depletion on pressor responsiveness in ACTH -induced hypertension in man.
2822310
1987
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Potentiation of ACTH hypertension in man with salt loading.
2992854
1985
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Children who develop hypertension during ACTH therapy should be considered at risk for hypertrophic cardiomyopathy and should undergo routine echocardiographic evaluation.
2821097
1987
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Overall, the data establish that the alpha(2)-Na(+)-K(+)-ATPase ouabain-binding site is of central importance in the development of ACTH -induced hypertension .
18487447
2008
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
These studies suggest that a steroid other than aldosterone, 18-OH-DOC, or DOC may be the cause of the ACTH -induced hypertension in this patient.
187612
1976
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
In man ACTH produces systolic hypertension which can be reproduced by infusion of cortisol, but not deoxycorticosterone, at rates appropriate for conditions of ACTH stimulation.
3001556
1985
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Partial characterization of unusual polar steroids in the urine of a child with low renin hypertension.
6283272
1982
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Atorvastatin prevented and partially reversed adrenocorticotropic hormone -induced hypertension in the rat.
16620303
2006
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Nitric oxide donation lowers blood pressure in adrenocorticotrophic hormone-induced hypertensive rats.
15554453
2004
×
Entrez Id:
5443
Gene Symbol:
POMC
POMC
Hypertensive disease
0.400
Biomarker
CTD_human
Role of nitric oxide in adrenocorticotrophin-induced hypertension: L-arginine effects reversed by N-nitro-L-arginine.
11071304
2000