Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human Cushing's syndrome secondary to ACTH-secreting Wilms' tumor. 4367732

1974
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human Cushing's syndrome secondary to ACTH-secreting Wilms' tumor. 4367732

1974
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human These studies suggest that a steroid other than aldosterone, 18-OH-DOC, or DOC may be the cause of the ACTH-induced hypertension in this patient. 187612

1976
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human These studies suggest that a steroid other than aldosterone, 18-OH-DOC, or DOC may be the cause of the ACTH-induced hypertension in this patient. 187612

1976
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human These studies suggest that an ACTH-dependent steroid rather than aldosterone, 18-OH-DOC, or DOC may be the cause of the hypertension in this patient. 323586

1977
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human These studies suggest that an ACTH-dependent steroid rather than aldosterone, 18-OH-DOC, or DOC may be the cause of the hypertension in this patient. 323586

1977
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human Exaggerated natriuresis in ACTH hypertension in sheep. 216942

1978
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human Dexamethasone-responsive hypertension in young women with suppressed renin and aldosterone. 76749

1978
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human Exaggerated natriuresis in ACTH hypertension in sheep. 216942

1978
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human Dexamethasone-responsive hypertension in young women with suppressed renin and aldosterone. 76749

1978
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human ACTH therapy in infantile spasms: side effects. 6254450

1980
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human ACTH therapy in infantile spasms: side effects. 6254450

1980
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human Effects of bromocriptine on blood pressure and plasma beta-endorphin in spontaneously hypertensive rats. 6274577

1981
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human Effects of bromocriptine on blood pressure and plasma beta-endorphin in spontaneously hypertensive rats. 6274577

1981
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human Alterations in osmotic but not pressor responses to ACTH by optic recess lesions in sheep. 6279500

1982
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human Partial characterization of unusual polar steroids in the urine of a child with low renin hypertension. 6283272

1982
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human Alterations in osmotic but not pressor responses to ACTH by optic recess lesions in sheep. 6279500

1982
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human Partial characterization of unusual polar steroids in the urine of a child with low renin hypertension. 6283272

1982
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human Vasodilator prostanoids and ACTH-dependent hypertension. 6135010

1983
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human Vasodilator prostanoids and ACTH-dependent hypertension. 6135010

1983
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human Based on the various biological effects of ACTH different explanations are proposed: oedema or deposition of glycogen in the myocardial tissue, hyperinsulinism, arterial hypertension and increased inotropic stimulus. 6088243

1984
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human Based on the various biological effects of ACTH different explanations are proposed: oedema or deposition of glycogen in the myocardial tissue, hyperinsulinism, arterial hypertension and increased inotropic stimulus. 6088243

1984
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Biomarker CTD_human Beta-endorphin contributes to the antihypertensive effect of clonidine in a subset of patients with essential hypertension. 6089027

1984
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human Beta-endorphin contributes to the antihypertensive effect of clonidine in a subset of patients with essential hypertension. 6089027

1984
Entrez Id: 5443
Gene Symbol: POMC
POMC
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.400 Therapeutic CTD_human Renal and pancreatic calcification during treatment of infantile spasms with ACTH. 6143199

1984