Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C4316903
Disease: Absence Seizures
Absence Seizures
0.300 Biomarker CTD_human Induction of proneurotrophins and activation of p75NTR-mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures. 18815271

2008

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0236663
Disease: Alcohol withdrawal syndrome
Alcohol withdrawal syndrome
0.310 Biomarker PSYGENET Epigenetic down regulation of nerve growth factor during alcohol withdrawal. 21392176

2013

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0458247
Disease: Allodynia
Allodynia
0.300 Biomarker CTD_human Hyperalgesic priming is restricted to isolectin B4-positive nociceptors. 20457222

2010

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0002622
Disease: Amnesia
Amnesia
0.310 Therapeutic CTD_human Brain targeting of nerve growth factor using poly(butyl cyanoacrylate) nanoparticles. 19694610

2009

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0002622
Disease: Amnesia
Amnesia
0.310 Therapeutic CTD_human The antiamnesic activity of nerve growth factor (NGF) in various medicinal forms [aqueous NGF solution with and without polysorbate-80 (PS-80) additives, NGF adsorbed on poly(butyl) cyanoacrylate (PBCA) nanoparticles with and without PS-80 coating] has been studied in rats with model amnesia induced by scopolamine (2 mg/kg, s.c.). 16405025

2006

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0750907
Disease: Amnestic State
Amnestic State
0.300 Therapeutic CTD_human Brain targeting of nerve growth factor using poly(butyl cyanoacrylate) nanoparticles. 19694610

2009

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0750907
Disease: Amnestic State
Amnestic State
0.300 Therapeutic CTD_human [Antiamnesic activity of nerve growth factor adsorbed on poly(butyl) cyanoacrylate nanoparticles coated with polysorbate-80]. 16405025

2006

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0751123
Disease: Atonic Absence Seizures
Atonic Absence Seizures
0.300 Biomarker CTD_human Induction of proneurotrophins and activation of p75NTR-mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures. 18815271

2008

Entrez Id: 4803
Gene Symbol: NGF
NGF
Autosomal Dominant Juvenile Parkinson Disease
0.300 Therapeutic CTD_human Brain targeting of nerve growth factor using poly(butyl cyanoacrylate) nanoparticles. 19694610

2009

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0752098
Disease: Autosomal Dominant Parkinsonism
Autosomal Dominant Parkinsonism
0.300 Therapeutic CTD_human Brain targeting of nerve growth factor using poly(butyl cyanoacrylate) nanoparticles. 19694610

2009

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0752100
Disease: Autosomal Recessive Parkinsonism
Autosomal Recessive Parkinsonism
0.300 Therapeutic CTD_human Brain targeting of nerve growth factor using poly(butyl cyanoacrylate) nanoparticles. 19694610

2009

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C1704377
Disease: Bright Disease
Bright Disease
0.300 Biomarker CTD_human Exposure to nerve growth factor worsens nephrotoxic effect induced by Cyclosporine A in HK-2 cells. 24244623

2013

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0085129
Disease: Bronchial Hyperreactivity
Bronchial Hyperreactivity
0.300 Biomarker CTD_human Blockage of nerve growth factor modulates T cell responses and inhibits allergic inflammation in a mouse model of asthma. 22871964

2012

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C1561643
Disease: Chronic Kidney Diseases
Chronic Kidney Diseases
0.300 Biomarker CTD_human Nerve growth factor serum concentrations increase during many inflammatory and autoimmune diseases, glomerulonephritis, chronic kidney disease, end-stage renal disease and, particularly, in renal transplant. 24244623

2013

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0403447
Disease: Chronic Kidney Insufficiency
Chronic Kidney Insufficiency
0.300 Biomarker CTD_human Exposure to nerve growth factor worsens nephrotoxic effect induced by Cyclosporine A in HK-2 cells. 24244623

2013

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C2350344
Disease: Chronic Lung Injury
Chronic Lung Injury
0.300 Therapeutic CTD_human Nerve growth factor enhances Clara cell proliferation after lung injury. 20075049

2010

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0234535
Disease: Clonic Seizures
Clonic Seizures
0.300 Biomarker CTD_human Induction of proneurotrophins and activation of p75NTR-mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures. 18815271

2008

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse
0.300 Biomarker CTD_human Chronic heroin and cocaine abuse is associated with decreased serum concentrations of the nerve growth factor and brain-derived neurotrophic factor. 17715210

2007

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence
0.300 Biomarker CTD_human Chronic heroin and cocaine abuse is associated with decreased serum concentrations of the nerve growth factor and brain-derived neurotrophic factor. 17715210

2007

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0236736
Disease: Cocaine-Related Disorders
Cocaine-Related Disorders
0.300 Biomarker CTD_human Chronic heroin and cocaine abuse is associated with decreased serum concentrations of the nerve growth factor and brain-derived neurotrophic factor. 17715210

2007

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0149958
Disease: Complex partial seizures
Complex partial seizures
0.300 Biomarker CTD_human Induction of proneurotrophins and activation of p75NTR-mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures. 18815271

2008

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0393734
Disease: Complex Partial Status Epilepticus
Complex Partial Status Epilepticus
0.300 Biomarker CTD_human Cellular hybridization for BDNF, trkB, and NGF mRNAs and BDNF-immunoreactivity in rat forebrain after pilocarpine-induced status epilepticus. 8821376

1996

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0393734
Disease: Complex Partial Status Epilepticus
Complex Partial Status Epilepticus
0.300 Biomarker CTD_human Change in neurotrophins and their receptor mRNAs in the rat forebrain after status epilepticus induced by pilocarpine. 8635431

1996

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C0002768
Disease: Congenital Pain Insensitivity
Congenital Pain Insensitivity
0.320 GermlineCausalMutation ORPHANET A mutation in the nerve growth factor beta gene (NGFB) causes loss of pain perception. 14976160

2004

Entrez Id: 4803
Gene Symbol: NGF
NGF
CUI: C4048158
Disease: Convulsions
Convulsions
0.300 Biomarker CTD_human Induction of proneurotrophins and activation of p75NTR-mediated apoptosis via neurotrophin receptor-interacting factor in hippocampal neurons after seizures. 18815271

2008