×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
GeneticVariation
BEFREE
11q13 translocation has been described in mantle cell lymphoma in the form of t(11;14) (q13;q32), with rearrangement and over-expression of the cyclin D1 gene.
10459355 1999
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
GeneticVariation
BEFREE
Mantle cell lymphoma (MCL) is characterized by the t(11;14) translocation resulting in deregulated cyclin D1 .12515730 2003
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
GeneticVariation
BEFREE
Mantle cell lymphomas are characterized by the t(11;14) (q13;q32) translocation and its molecular counterpart bcl-1 rearrangement.1490145 1992
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
GeneticVariation
BEFREE
Mantle cell lymphoma is a distinct entity among the non-Hodgkin's lymphomas characterized by a specific chromosomal translocation, the t(11;14)(q13;q32) , overexpression of cyclin-D1 and frequent disease manifestations at extranodal sites.16001955 2005
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
GeneticVariation
BEFREE
Mantle cell lymphoma in Taiwan: clinicopathological and molecular study of 21 cases including one cyclin D1 -negative tumor expressing cyclin D2.16872438 2006
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
Mantle cell lymphoma is a B cell malignancy in which constitutive dysregulation of cyclin D1 and the cell cycle, disruption of DNA damage response pathways, and activation of cell survival mechanisms contribute to oncogenesis.23023712 2012
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
GeneticVariation
BEFREE
Mantle cell lymphoma with a novel t(11;12)(q13;p11.2) : a proposed alternative mechanism of CCND1 up-regulation.28132860 2017
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
GeneticVariation
BEFREE
Mantle cell lymphoma is a B cell lymphoproliferative disorder cytogenetically characterized by the t(11;14)(q13;q32) which at molecular level involves the Bcl-1 /PRAD-1 gene.8649059 1996
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
GeneticVariation
BEFREE
Mantle cell lymphoma is strongly associated with the t(11;14) chromosomal translocation that rearranges the bcl-1 oncogene (PRAD-1 gene) and immunoglobulin heavy chain gene.8729972 1996
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
Mantle cell lymphoma is a distinct clinicopathological entity associated with t(11;14) and cyclin D1 overexpression.9753060 1998
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
Cyclin-D1 mRNA was expressed in patients with mantle-cell lymphoma (MCL; 10/10), hairy-cell leukemia (HCL; 3/5), B-chronic lymphoid leukemia (B-CLL; 4/111) and B large-cell lymphoma (BLCL; 1/1).10471532 1999
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
Cyclin D1 expression is deregulated by chromosome translocation in mantle cell lymphoma and a subset of multiple myeloma.15226187 2004
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
Cyclin D1 is a positive cell cycle regulator that is overexpressed in a variety of neoplasms, including mantle cell lymphoma and breast carcinoma.15578074 2005
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
BEFREE
Cyclin D1 immunohistochemical staining is usually envisioned as a definitive method for resolving this differential diagnosis, with positivity supporting a diagnosis of mantle cell lymphoma .15628916 2005
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
LHGDN
Cyclin D1 -negative mantle cell lymphoma : a clinicopathologic study based on gene expression profiling.16123218 2005
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
BEFREE
Cyclin D1 -negative mantle cell lymphoma : a clinicopathologic study based on gene expression profiling.16123218 2005
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
Cyclin D1 mRNA isoforms a and b were expressed in mantle cell lymphoma (MCL) and multiple myeloma (MM).17022831 2006
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
LHGDN
Cyclin D1 mRNA isoforms a and b were expressed in mantle cell lymphoma (MCL) and multiple myeloma (MM).17022831 2006
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
GeneticVariation
BEFREE
Cyclin D1 and t(11;14)-positive B-cell neoplasms resembling marginal zone B-cell lymphoma: a morphological variant of mantle cell lymphoma .17316759 2007
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
Cyclin-D1 , D2 and D3 were expressed in 100, 22 and 6% of mantle-cell lymphomas and 2, 49 and 20% of diffuse large B-cell lymphomas.20062012 2010
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
GeneticVariation
BEFREE
CCND1 (+)/MYC(+) DH lymphomas with involvement of 11q13 may also be relatively frequent, the great majority being classified as aggressive variants of mantle cell lymphoma .21119107 2011
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
Cyclin D1 overexpression is a hallmark of mantle cell lymphoma , whereas cyclins D2 and D3 have not been shown to be closely associated with any particular subtype of lymphoma.21790895 2011
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
BEFREE
Cyclin D1 -negative mantle cell lymphoma .23429984 2013
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
Cyclin D1 (CCND1 ) messenger RNA expression as assessed by real-time PCR contributes to diagnosis and follow-up control in patients with mantle cell lymphoma .24060591 2013
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
BEFREE
Cyclin D1 depletion induces DNA damage in mantle cell lymphoma lines.27338091 2017