Source: CLINVAR

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.100 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 5295
Gene Symbol: PIK3R1
PIK3R1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.100 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 1387
Gene Symbol: CREBBP
CREBBP
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.100 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 5518
Gene Symbol: PPP2R1A
PPP2R1A
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.100 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 7514
Gene Symbol: XPO1
XPO1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.100 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 3418
Gene Symbol: IDH2
IDH2
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.100 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.110 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 567
Gene Symbol: B2M
B2M
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.110 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 387
Gene Symbol: RHOA
RHOA
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.110 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.110 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.110 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.120 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 5604
Gene Symbol: MAP2K1
MAP2K1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.120 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 2778
Gene Symbol: GNAS
GNAS
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.130 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 5894
Gene Symbol: RAF1
RAF1
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.130 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.160 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.160 CausalMutation CLINVAR Phase I, dose-escalation study of BKM120, an oral pan-Class I PI3K inhibitor, in patients with advanced solid tumors. 22162589

2012
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.160 CausalMutation CLINVAR Phosphatidylinositide-3-kinase inhibitors: addressing questions of isoform selectivity and pharmacodynamic/predictive biomarkers in early clinical trials. 22162582

2012
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.160 CausalMutation CLINVAR Predictive biomarkers of sensitivity to the phosphatidylinositol 3' kinase inhibitor GDC-0941 in breast cancer preclinical models. 20453058

2010
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.160 CausalMutation CLINVAR Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis. 20619739

2010
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.160 CausalMutation CLINVAR PIK3CA mutations predict local recurrences in rectal cancer patients. 19903786

2009
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.160 CausalMutation CLINVAR PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal cancer. 19366826

2009
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.160 CausalMutation CLINVAR Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling. 18725974

2008
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.160 CausalMutation CLINVAR Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic. 15647370

2005
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.160 CausalMutation CLINVAR High frequency of mutations of the PIK3CA gene in human cancers. 15016963

2004