×
Entrez Id: 9001
Gene Symbol: HAP1
HAP1
Unipolar Depression
0.200
Biomarker
MGD
×
Entrez Id: 5320
Gene Symbol: PLA2G2A
PLA2G2A
Unipolar Depression
0.010
Biomarker
BEFREE
'Mom-I don't want to hear it': Brain response to maternal praise and criticism in adolescents with major depressive disorder .
28338795 2017
×
Entrez Id: 6530
Gene Symbol: SLC6A2
SLC6A2
Unipolar Depression
0.400
GeneticVariation
BEFREE
252 unrelated Caucasian patients (f = 142; m = 110) with major depression were genotyped for NET and 5-HTT polymorphisms.
20588071 2010
×
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
Unipolar Depression
0.600
GeneticVariation
BEFREE
252 unrelated Caucasian patients (f = 142; m = 110) with major depression were genotyped for NET and 5-HTT polymorphisms.
20588071 2010
×
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
Unipolar Depression
0.380
Biomarker
PSYGENET
47 patients with Major Depressive Disorder , treated with V 75 - 300 mg/day, underwent CYP2D6 genotyping using the INFINITI-CYP2D6 assay.
24660534 2014
×
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
Unipolar Depression
0.600
GeneticVariation
BEFREE
49 patients with major depression and SSRI treatment were genotyped for the 5-HTTLPR locus including the rs25531 .
22086748 2012
×
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A
Unipolar Depression
0.400
Biomarker
BEFREE
5-HTR1A , 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression .
19590397 2009
×
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
Unipolar Depression
0.400
GeneticVariation
BEFREE
5-HTR1A, 5-HTR2A , 5-HTR6, TPH1 and TPH2 polymorphisms and major depression .
19590397 2009
×
Entrez Id: 121278
Gene Symbol: TPH2
TPH2
Unipolar Depression
0.800
GeneticVariation
BEFREE
5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression .
19590397 2009
×
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR
Unipolar Depression
0.600
GeneticVariation
BEFREE
5-HTTLPR and <i>MTHFR 677C</i>>T polymorphisms and response to yoga-based lifestyle intervention in major depressive disorder : A randomized active-controlled trial.
30581206 2020
×
Entrez Id: 3776
Gene Symbol: KCNK2
KCNK2
Unipolar Depression
0.330
Biomarker
CTD_human
5-HTTLPR genotype and gender, but not chronic fluoxetine administration, are associated with cortical TREK1 protein expression in rhesus macaques.
21871532 2011
×
Entrez Id: 4128
Gene Symbol: MAOA
MAOA
Unipolar Depression
0.400
Biomarker
PSYGENET
94 patients of Caucasian descent with major depressive disorder (f = 61; DSM-IV) were analyzed for DNA methylation status at 43 MAO-A CpG sites via direct sequencing of sodium bisulfite treated DNA extracted from blood cells.
24809685 2015
×
Entrez Id: 4128
Gene Symbol: MAOA
MAOA
Unipolar Depression
0.400
PosttranslationalModification
BEFREE
94 patients of Caucasian descent with major depressive disorder (f = 61; DSM-IV) were analyzed for DNA methylation status at 43 MAO-A CpG sites via direct sequencing of sodium bisulfite treated DNA extracted from blood cells.
24809685 2015
×
Entrez Id: 627
Gene Symbol: BDNF
BDNF
Unipolar Depression
0.600
AlteredExpression
BEFREE
: The results suggest that the existence of major depression in pregnant women may negatively affect fetal circulating BDNF levels.
30905131 2019
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Unipolar Depression
0.090
Biomarker
BEFREE
Major depression is an important comorbidity in Alzheimer's disease, which is definitely associated with the apolipoprotein E (apo E) polymorphism.16390369 2006
×
Entrez Id: 4128
Gene Symbol: MAOA
MAOA
Unipolar Depression
0.400
GeneticVariation
BEFREE
Major depressive disorder is a mediating factor between the monoamine oxidase A promoter polymorphism and telomeric length.17417064 2007
×
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1
Unipolar Depression
0.600
GeneticVariation
BEFREE
Unipolar depression is associated with DNA variants of the NR3C1 gene in our population.18286599 2008
×
Entrez Id: 2332
Gene Symbol: FMR1
FMR1
Unipolar Depression
0.310
Biomarker
PSYGENET
Major depression in females with the FMR1 premutation may not be characterized as an episodically chronic recurrent disorder as it is in community samples and may have a genetic basis given the relationship with CGG repeat length and lack of association with all child and most demographic factors.18553360 2009
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Unipolar Depression
0.600
AlteredExpression
BEFREE
Major depressive disorder is a condition associated with dysregulated cytokine levels; among these, IL6 .27796193 2017
×
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
Unipolar Depression
0.030
GeneticVariation
BEFREE
Major depressive disorder -associated SIRT1 locus affects the risk for suicide in women after middle age.31176830 2019
×
Entrez Id: 5999
Gene Symbol: RGS4
RGS4
Unipolar Depression
0.020
AlteredExpression
BEFREE
RGS4 expression was not altered in the prefrontal cortex of subjects with major depressive disorder or in monkeys treated chronically with haloperidol.11326297 2001
×
Entrez Id: 57113
Gene Symbol: TRPC7
TRPC7
Unipolar Depression
0.010
AlteredExpression
BEFREE
TRPC7 mRNA levels were significantly lower in BLCLs from BD-I patients with high BLCL [Ca(2+)]B compared with those showing normal [Ca(2+)]B (-33%, p =.017) and with BD-II patients (-48%, p =.003), major depressive disorder patients (-47%, p =.049) and healthy subjects (-33%, p =.038).11690598 2001
×
Entrez Id: 4049
Gene Symbol: LTA
LTA
Unipolar Depression
0.310
GeneticVariation
BEFREE
Tumor necrosis factor-beta gene polymorphism may not be associated with major depressive disorder in the Korean population.12519452 2003
×
Entrez Id: 348
Gene Symbol: APOE
APOE
Unipolar Depression
0.090
GeneticVariation
BEFREE
Apolipoprotein E genotype and major depression in a community of older adults. The Cache County Study.12701674 2003
×
Entrez Id: 153
Gene Symbol: ADRB1
ADRB1
Unipolar Depression
0.010
Biomarker
BEFREE
Beta-1-adrenergic receptor gene in major depression : influence on antidepressant treatment response.12815745 2003