Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0353676
Disease: Organophosphorus Poisoning
Organophosphorus Poisoning 		0.300 Biomarker CTD_human Dichlorvos toxicity in the white-footed mouse (Peromyscus leucopus). 3669600

1987
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0353676
Disease: Organophosphorus Poisoning
Organophosphorus Poisoning 		0.300 Therapeutic CTD_human Dichlorvos toxicity in the white-footed mouse (Peromyscus leucopus). 3669600

1987
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0700359
Disease: Organophosphate poisoning
Organophosphate poisoning 		0.300 Biomarker CTD_human Dichlorvos toxicity in the white-footed mouse (Peromyscus leucopus). 3669600

1987
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0700359
Disease: Organophosphate poisoning
Organophosphate poisoning 		0.300 Therapeutic CTD_human Dichlorvos toxicity in the white-footed mouse (Peromyscus leucopus). 3669600

1987
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C3494247
Disease: Organothiophosphonate Poisoning
Organothiophosphonate Poisoning 		0.300 Biomarker CTD_human Dichlorvos toxicity in the white-footed mouse (Peromyscus leucopus). 3669600

1987
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C3494247
Disease: Organothiophosphonate Poisoning
Organothiophosphonate Poisoning 		0.300 Therapeutic CTD_human Dichlorvos toxicity in the white-footed mouse (Peromyscus leucopus). 3669600

1987
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C3494248
Disease: Organothiophosphate Poisoning
Organothiophosphate Poisoning 		0.300 Biomarker CTD_human Dichlorvos toxicity in the white-footed mouse (Peromyscus leucopus). 3669600

1987
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C3494248
Disease: Organothiophosphate Poisoning
Organothiophosphate Poisoning 		0.300 Therapeutic CTD_human Dichlorvos toxicity in the white-footed mouse (Peromyscus leucopus). 3669600

1987
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0353676
Disease: Organophosphorus Poisoning
Organophosphorus Poisoning 		0.300 Therapeutic CTD_human Comparative efficacy of exogenous acetylcholinesterase administration on soman and dichlorvos toxicity in rats. 8359835

1993
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0353676
Disease: Organophosphorus Poisoning
Organophosphorus Poisoning 		0.300 Biomarker CTD_human Comparative efficacy of exogenous acetylcholinesterase administration on soman and dichlorvos toxicity in rats. 8359835

1993
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0700359
Disease: Organophosphate poisoning
Organophosphate poisoning 		0.300 Biomarker CTD_human Comparative efficacy of exogenous acetylcholinesterase administration on soman and dichlorvos toxicity in rats. 8359835

1993
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0700359
Disease: Organophosphate poisoning
Organophosphate poisoning 		0.300 Therapeutic CTD_human Comparative efficacy of exogenous acetylcholinesterase administration on soman and dichlorvos toxicity in rats. 8359835

1993
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C3494247
Disease: Organothiophosphonate Poisoning
Organothiophosphonate Poisoning 		0.300 Therapeutic CTD_human Comparative efficacy of exogenous acetylcholinesterase administration on soman and dichlorvos toxicity in rats. 8359835

1993
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C3494247
Disease: Organothiophosphonate Poisoning
Organothiophosphonate Poisoning 		0.300 Biomarker CTD_human Comparative efficacy of exogenous acetylcholinesterase administration on soman and dichlorvos toxicity in rats. 8359835

1993
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C3494248
Disease: Organothiophosphate Poisoning
Organothiophosphate Poisoning 		0.300 Biomarker CTD_human Comparative efficacy of exogenous acetylcholinesterase administration on soman and dichlorvos toxicity in rats. 8359835

1993
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C3494248
Disease: Organothiophosphate Poisoning
Organothiophosphate Poisoning 		0.300 Therapeutic CTD_human Comparative efficacy of exogenous acetylcholinesterase administration on soman and dichlorvos toxicity in rats. 8359835

1993
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental 		0.300 Biomarker CTD_human Changes in liver and plasma acetylcholinesterase in rats with cirrhosis induced by bile duct ligation. 16496349

2006
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0236733
Disease: Amphetamine-Related Disorders
Amphetamine-Related Disorders 		0.300 Biomarker CTD_human Genetic identification of AChE as a positive modulator of addiction to the psychostimulant D-amphetamine in zebrafish. 16470869

2006
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0236804
Disease: Amphetamine Addiction
Amphetamine Addiction 		0.300 Biomarker CTD_human Genetic identification of AChE as a positive modulator of addiction to the psychostimulant D-amphetamine in zebrafish. 16470869

2006
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0236807
Disease: Amphetamine Abuse
Amphetamine Abuse 		0.300 Biomarker CTD_human Genetic identification of AChE as a positive modulator of addiction to the psychostimulant D-amphetamine in zebrafish. 16470869

2006
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0233794
Disease: Memory impairment
Memory impairment 		0.400 Biomarker CTD_human Release of acetylcholinesterase (AChE) from beta-amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice. 18599028

2008
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0007134
Disease: Renal Cell Carcinoma
Renal Cell Carcinoma 		0.310 Biomarker CTD_human The expression of cholinesterases in human renal tumours varies according to their histological types. 18482720

2008
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0025261
Disease: Memory Disorders
Memory Disorders 		0.310 Biomarker CTD_human Release of acetylcholinesterase (AChE) from beta-amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice. 18599028

2008
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0751295
Disease: Memory Loss
Memory Loss 		0.310 Biomarker CTD_human Release of acetylcholinesterase (AChE) from beta-amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice. 18599028

2008
Entrez Id: 43
Gene Symbol: ACHE
ACHE
CUI: C0023186
Disease: Learning Disorders
Learning Disorders 		0.300 Biomarker CTD_human Hyposensitivity to the amnesic effects of scopolamine or amyloid beta(25-35) peptide in heterozygous acetylcholinesterase knockout (AChE(+/-)) mice. 18533140

2008