Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease 		0.680 Biomarker CTD_human

Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C1866423
Disease: Quebec platelet disorder
Quebec platelet disorder 		0.670 Biomarker CTD_human

Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C1866423
Disease: Quebec platelet disorder
Quebec platelet disorder 		0.670 Biomarker GENOMICS_ENGLAND QPD is the first bleeding disorder to be associated with a gene duplication event and a PLAU mutation. 20007542

2010
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C1866423
Disease: Quebec platelet disorder
Quebec platelet disorder 		0.670 GermlineCausalMutation ORPHANET QPD is the first bleeding disorder to be associated with a gene duplication event and a PLAU mutation. 20007542

2010
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Biomarker CTD_human Intravenous urokinase in acute myocardial infarction. 3984876

1985
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Therapeutic CTD_human [Use of urokinase in acute myocardial infarction]. 3068399

1988
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Therapeutic CTD_human Unstable angina or non-Q wave infarction despite long-term aspirin: response to thrombolytic therapy with implications on mechanisms. 2382605

1990
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Therapeutic CTD_human Acute myocardial infarction complicating urokinase infusion for total saphenous vein graft occlusion. 8416330

1993
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Biomarker CTD_human Femoral nerve palsy secondary to anticoagulant induced iliacus hematoma. A case report. 2174952

1991
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Biomarker CTD_human Acute myocardial infarction complicating urokinase infusion for total saphenous vein graft occlusion. 8416330

1993
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Therapeutic CTD_human [The kinetics of plasma coagulation fibrinolysis levels in acute myocardial infarction before and after treatment with intravenous urokinase]. 1908371

1991
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Biomarker CTD_human Unstable angina or non-Q wave infarction despite long-term aspirin: response to thrombolytic therapy with implications on mechanisms. 2382605

1990
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Biomarker CTD_human [Use of urokinase in acute myocardial infarction]. 3068399

1988
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Biomarker CTD_human [The kinetics of plasma coagulation fibrinolysis levels in acute myocardial infarction before and after treatment with intravenous urokinase]. 1908371

1991
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Therapeutic CTD_human Femoral nerve palsy secondary to anticoagulant induced iliacus hematoma. A case report. 2174952

1991
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction 		0.510 Therapeutic CTD_human Intravenous urokinase in acute myocardial infarction. 3984876

1985
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental 		0.500 Biomarker CTD_human Systems level analysis and identification of pathways and networks associated with liver fibrosis. 25380136

2014
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0035126
Disease: Reperfusion Injury
Reperfusion Injury 		0.500 Therapeutic CTD_human [Effectiveness of urokinase used in combination with batroxobin (DF-521) in rat model of focal cerebral ischemia-reperfusion]. 15181847

2004
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0040053
Disease: Thrombosis
Thrombosis 		0.500 Therapeutic CTD_human [Preparation of thrombus-targeted urokinase liposomes and its thrombolytic effect in model rats]. 12830724

2003
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0040053
Disease: Thrombosis
Thrombosis 		0.500 Therapeutic CTD_human Intraoperative infusion of lytic drugs for thrombotic complications of revascularization. 2795766

1989
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0040053
Disease: Thrombosis
Thrombosis 		0.500 Therapeutic CTD_human Urokinase and AT-III concentrate treatment in inferior vena cava thrombosis associated with nephrotic syndrome. 2133253

1990
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0040053
Disease: Thrombosis
Thrombosis 		0.500 Therapeutic CTD_human [Treatment of massive arterial thrombosis caused by thrombocytopenia induced by heparin with local thrombolysis]. 2106299

1990
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0040053
Disease: Thrombosis
Thrombosis 		0.500 Therapeutic CTD_human The urokinase-pulmonary embolism trial. 4884574

1969
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0040053
Disease: Thrombosis
Thrombosis 		0.500 Therapeutic CTD_human Pulmonary emboli from pulse-spray and mechanical thrombolysis: evaluation with an animal dialysis-graft model. 8657906

1996
Entrez Id: 5328
Gene Symbol: PLAU
PLAU
CUI: C0151699
Disease: Intracranial Hemorrhage
Intracranial Hemorrhage 		0.500 Biomarker CTD_human Low- versus high-dose recombinant urokinase for the treatment of chronic saphenous vein graft occlusion. 10392865

1999