Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0587248
Disease: Costello syndrome (disorder)
Costello syndrome (disorder) 		1.000 Biomarker CTD_human Further evidence of genetic heterogeneity in Costello syndrome: involvement of the KRAS gene. 17468812

2007
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0587248
Disease: Costello syndrome (disorder)
Costello syndrome (disorder) 		1.000 Biomarker CTD_human Expression of H-RASV12 in a zebrafish model of Costello syndrome causes cellular senescence in adult proliferating cells. 19132118

2009
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0587248
Disease: Costello syndrome (disorder)
Costello syndrome (disorder) 		1.000 Biomarker CTD_human Cardiofaciocutaneous (CFC) syndrome associated with muscular coenzyme Q10 deficiency. 17703371

2007
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0025202
Disease: melanoma
melanoma 		0.800 Biomarker CTD_human Ras-Induced miR-146a and 193a Target Jmjd6 to Regulate Melanoma Progression. 30619488

2018
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C4552097
Disease: Nevus Sebaceus of Jadassohn
Nevus Sebaceus of Jadassohn 		0.720 Biomarker CTD_human Postzygotic HRAS and KRAS mutations cause nevus sebaceous and Schimmelpenning syndrome. 22683711

2012
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0265329
Disease: Organoid Nevus Phakomatosis
Organoid Nevus Phakomatosis 		0.710 Biomarker CTD_human Mosaicism for HRAS c.37G>C and KRAS c.35G>A mutations was found in two individuals with Schimmelpenning syndrome. 22683711

2012
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0005684
Disease: Malignant neoplasm of urinary bladder
Malignant neoplasm of urinary bladder 		0.700 Biomarker CTD_human Activating missense mutations in Ha-ras-1 genes in a malignant subset of bladder lesions induced by N-butyl-N-(4-hydroxybutyl)nitrosamine or N-[4-(5-nitro-2-furanyl)-2-thiazolyl]formamide. 2278634

1990
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0005684
Disease: Malignant neoplasm of urinary bladder
Malignant neoplasm of urinary bladder 		0.700 Biomarker CTD_human Oncogene expression of FANFT- or BBN-induced rat urothelial cells. 2228319

1990
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0005684
Disease: Malignant neoplasm of urinary bladder
Malignant neoplasm of urinary bladder 		0.700 Biomarker CTD_human High susceptibility of human c-Ha-ras proto-oncogene transgenic rats to carcinogenesis: a cancer-prone animal model. 15958052

2005
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0028326
Disease: Noonan Syndrome
Noonan Syndrome 		0.640 Biomarker CTD_human Cardiofaciocutaneous (CFC) syndrome associated with muscular coenzyme Q10 deficiency. 17703371

2007
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.600 Biomarker CTD_human Activating missense mutations in Ha-ras-1 genes in a malignant subset of bladder lesions induced by N-butyl-N-(4-hydroxybutyl)nitrosamine or N-[4-(5-nitro-2-furanyl)-2-thiazolyl]formamide. 2278634

1990
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.600 Biomarker CTD_human Oncogene expression of FANFT- or BBN-induced rat urothelial cells. 2228319

1990
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0005695
Disease: Bladder Neoplasm
Bladder Neoplasm 		0.600 Biomarker CTD_human High susceptibility of human c-Ha-ras proto-oncogene transgenic rats to carcinogenesis: a cancer-prone animal model. 15958052

2005
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 Biomarker CTD_human Increased H-ras mutation frequency in mammary tumors of rats initiated with N-methyl-N-nitrosourea (MNU) and treated with acrylamide. 19652463

2009
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 Biomarker CTD_human Frequent mutations of the Trp53, Hras1 and beta-catenin (Catnb) genes in 1,3-butadiene-induced mammary adenocarcinomas in B6C3F1 mice. 12165863

2002
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 Biomarker CTD_human Possible application of human c-Ha-ras proto-oncogene transgenic rats in a medium-term bioassay model for carcinogens. 17474063

2007
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.600 Biomarker CTD_human High susceptibility of human c-Ha-ras proto-oncogene transgenic rats to carcinogenesis: a cancer-prone animal model. 15958052

2005
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.600 Biomarker CTD_human Functional kinomics identifies candidate therapeutic targets in head and neck cancer. 25125259

2014
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0007137
Disease: Squamous cell carcinoma
Squamous cell carcinoma 		0.600 Biomarker CTD_human Common oncogenic mutations are infrequent in oral squamous cell carcinoma of Asian origin. 24224046

2013
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		0.600 Biomarker CTD_human Mutational dynamics between primary and relapse neuroblastomas. 26121086

2015
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0027819
Disease: Neuroblastoma
Neuroblastoma 		0.600 Biomarker CTD_human Genetic alterations in brain tumors following 1,3-butadiene exposure in B6C3F1 mice. 15814359

2005
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.600 Biomarker CTD_human Frequent mutations of the Trp53, Hras1 and beta-catenin (Catnb) genes in 1,3-butadiene-induced mammary adenocarcinomas in B6C3F1 mice. 12165863

2002
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.600 Biomarker CTD_human High susceptibility of human c-Ha-ras proto-oncogene transgenic rats to carcinogenesis: a cancer-prone animal model. 15958052

2005
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.600 Biomarker CTD_human Increased H-ras mutation frequency in mammary tumors of rats initiated with N-methyl-N-nitrosourea (MNU) and treated with acrylamide. 19652463

2009
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.600 Biomarker CTD_human Possible application of human c-Ha-ras proto-oncogene transgenic rats in a medium-term bioassay model for carcinogens. 17474063

2007