Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C1275081
Disease: Cardio-facio-cutaneous syndrome
Cardio-facio-cutaneous syndrome 		0.570 Biomarker CTD_human Cardiofaciocutaneous (CFC) syndrome associated with muscular coenzyme Q10 deficiency. 17703371

2007
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0549473
Disease: Thyroid carcinoma
Thyroid carcinoma 		0.560 Biomarker CTD_human Agent-specific ras oncogene activation in rat thyroid tumours. 3078959

1988
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0007138
Disease: Carcinoma, Transitional Cell
Carcinoma, Transitional Cell 		0.530 Biomarker CTD_human Enhanced expression of Harvey-ras oncogene in FANFT-induced transitional cell carcinoma. 3433577

1987
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0017638
Disease: Glioma
Glioma 		0.520 Biomarker CTD_human Ras-Induced miR-146a and 193a Target Jmjd6 to Regulate Melanoma Progression. 30619488

2018
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental 		0.500 Biomarker CTD_human Infrequent mutation of Ha-ras and p53 in rat mammary carcinomas induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. 8185828

1994
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0024668
Disease: Mammary Neoplasms, Experimental
Mammary Neoplasms, Experimental 		0.500 Biomarker CTD_human High susceptibility of transgenic rats carrying the human c-Ha-ras proto-oncogene to chemically-induced mammary carcinogenesis. 11376698

2001
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0026640
Disease: Mouth Neoplasms
Mouth Neoplasms 		0.500 Biomarker CTD_human Common oncogenic mutations are infrequent in oral squamous cell carcinoma of Asian origin. 24224046

2013
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0030354
Disease: Papilloma
Papilloma 		0.500 Biomarker CTD_human Chemically induced skin carcinogenesis in a transgenic mouse line (TG.AC) carrying a v-Ha-ras gene. 8330346

1993
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder) 		0.500 Biomarker CTD_human Gene expression analysis in the lung of the rasH2 transgenic mouse at week 4 prior to induction of malignant tumor formation by urethane and N-methylolacrylamide. 26558449

2015
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0555198
Disease: Malignant Glioma
Malignant Glioma 		0.500 Biomarker CTD_human Ras-Induced miR-146a and 193a Target Jmjd6 to Regulate Melanoma Progression. 30619488

2018
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.500 Biomarker CTD_human At week 16, rats that had received the mutated Ha-ras antisense oligonucleotides had significantly fewer and smaller preneoplastic lesions positive for glutathione-S-transferase, placental type, and had smaller hepatocellular carcinomas than rats that had received the sense oligonucleotide. 9311599

1997
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.500 Biomarker CTD_human Wnt/beta-catenin signaling activates and determines hepatic zonal expression of glutathione S-transferases in mouse liver. 20118494

2010
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.500 Biomarker CTD_human Computational Discovery of Niclosamide Ethanolamine, a Repurposed Drug Candidate That Reduces Growth of Hepatocellular Carcinoma Cells In Vitro and in Mice by Inhibiting Cell Division Cycle 37 Signaling. 28284560

2017
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.500 Biomarker CTD_human Peroxiredoxin I is important for cancer-cell survival in Ras-induced hepatic tumorigenesis. 27517622

2016
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma 		0.500 Biomarker CTD_human Low frequency of H-ras mutations in hepatocellular adenomas and carcinomas and in hepatoblastomas from B6C3F1 mice exposed to oxazepam in the diet. 8200073

1994
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0040136
Disease: Thyroid Neoplasm
Thyroid Neoplasm 		0.460 Biomarker CTD_human Agent-specific ras oncogene activation in rat thyroid tumours. 3078959

1988
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.450 Biomarker CTD_human Possible application of human c-Ha-ras proto-oncogene transgenic rats in a medium-term bioassay model for carcinogens. 17474063

2007
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.450 Biomarker CTD_human Increased H-ras mutation frequency in mammary tumors of rats initiated with N-methyl-N-nitrosourea (MNU) and treated with acrylamide. 19652463

2009
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.450 Biomarker CTD_human High susceptibility of human c-Ha-ras proto-oncogene transgenic rats to carcinogenesis: a cancer-prone animal model. 15958052

2005
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.450 Biomarker CTD_human Frequent mutations of the Trp53, Hras1 and beta-catenin (Catnb) genes in 1,3-butadiene-induced mammary adenocarcinomas in B6C3F1 mice. 12165863

2002
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0334082
Disease: NEVUS, EPIDERMAL (disorder)
NEVUS, EPIDERMAL (disorder) 		0.420 Biomarker CTD_human

Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0007097
Disease: Carcinoma
Carcinoma 		0.400 Biomarker CTD_human Single-strand conformation polymorphism (SSCP) analysis and direct sequencing demonstrated a G-->A transition at the second position of Ha-ras codon 12, with the resultant substitution of glutamic acid for glycine, in two of 10 carcinomas induced by 100 ppm PhIP and in one of seven induced by the 400 ppm dose. 8185828

1994
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0010606
Disease: Adenoid Cystic Carcinoma
Adenoid Cystic Carcinoma 		0.400 Biomarker CTD_human The mutational landscape of adenoid cystic carcinoma. 23685749

2013
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.400 Biomarker CTD_human Susceptibilities of p53 knockout and rasH2 transgenic mice to urethane-induced lung carcinogenesis are inherited from their original strains. 15902970

2005
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
CUI: C0242379
Disease: Malignant neoplasm of lung
Malignant neoplasm of lung 		0.400 Biomarker CTD_human Mutation analysis of vinyl carbamate or urethane induced lung tumors in rasH2 transgenic mice. 12765245

2003