Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Biomarker CTD_human Regression of left ventricular hypertrophy in human hypertension with irbesartan. 11403367

2001
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Therapeutic CTD_human Regression of left ventricular hypertrophy in human hypertension with irbesartan. 11403367

2001
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Biomarker CTD_human Heme oxygenase-1 inhibits angiotensin II-induced cardiac hypertrophy in vitro and in vivo. 15226216

2004
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Therapeutic CTD_human Heme oxygenase-1 inhibits angiotensin II-induced cardiac hypertrophy in vitro and in vivo. 15226216

2004
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Biomarker CTD_human Cyclooxygenase-2 inhibitors attenuate angiotensin II-induced oxidative stress, hypertension, and cardiac hypertrophy in rats. 15851630

2005
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Therapeutic CTD_human Cyclooxygenase-2 inhibitors attenuate angiotensin II-induced oxidative stress, hypertension, and cardiac hypertrophy in rats. 15851630

2005
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Biomarker CTD_human Requirement of nuclear factor-kappaB in angiotensin II- and isoproterenol-induced cardiac hypertrophy in vivo. 15870116

2005
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Therapeutic CTD_human Requirement of nuclear factor-kappaB in angiotensin II- and isoproterenol-induced cardiac hypertrophy in vivo. 15870116

2005
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Therapeutic CTD_human Carbonic anhydrase inhibition prevents and reverts cardiomyocyte hypertrophy. 17124262

2007
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Biomarker CTD_human Carbonic anhydrase inhibition prevents and reverts cardiomyocyte hypertrophy. 17124262

2007
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Biomarker CTD_human Simvastatin prevents cardiac hypertrophy in vitro and in vivo via JAK/STAT pathway. 18400235

2008
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Therapeutic CTD_human Simvastatin prevents cardiac hypertrophy in vitro and in vivo via JAK/STAT pathway. 18400235

2008
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Biomarker CTD_human 3,3',4',5,7-Pentamethylquercetin reduces angiotensin II-induced cardiac hypertrophy and apoptosis in rats. 19794523

2009
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Therapeutic CTD_human 3,3',4',5,7-Pentamethylquercetin reduces angiotensin II-induced cardiac hypertrophy and apoptosis in rats. 19794523

2009
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Biomarker CTD_human Angiotensin-(1-7) stimulates high atrial pacing-induced ANP secretion via Mas/PI3-kinase/Akt axis and Na+/H+ exchanger. 20190099

2010
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Therapeutic CTD_human Angiotensin-(1-7) stimulates high atrial pacing-induced ANP secretion via Mas/PI3-kinase/Akt axis and Na+/H+ exchanger. 20190099

2010
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Therapeutic CTD_human Reduced isoproterenol-induced renin-angiotensin changes and extracellular matrix deposition in hearts of TGR(A1-7)3292 rats. 20409916

2013
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Biomarker CTD_human Reduced isoproterenol-induced renin-angiotensin changes and extracellular matrix deposition in hearts of TGR(A1-7)3292 rats. 20409916

2013
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Therapeutic CTD_human Resveratrol induces mitochondrial biogenesis and ameliorates Ang II-induced cardiac remodeling in transgenic rats harboring human renin and angiotensinogen genes. 20429690

2010
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Biomarker CTD_human Resveratrol induces mitochondrial biogenesis and ameliorates Ang II-induced cardiac remodeling in transgenic rats harboring human renin and angiotensinogen genes. 20429690

2010
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Therapeutic CTD_human The IP3 receptor regulates cardiac hypertrophy in response to select stimuli. 20616315

2010
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Biomarker CTD_human The IP3 receptor regulates cardiac hypertrophy in response to select stimuli. 20616315

2010
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Therapeutic CTD_human Levosimendan improves cardiac function and survival in rats with angiotensin II-induced hypertensive heart failure. 20811386

2010
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Biomarker CTD_human Levosimendan improves cardiac function and survival in rats with angiotensin II-induced hypertensive heart failure. 20811386

2010
Entrez Id: 183
Gene Symbol: AGT
AGT
CUI: C0018800
Disease: Cardiomegaly
Cardiomegaly 		0.500 Biomarker CTD_human The epidermal growth factor receptor is involved in angiotensin II but not aldosterone/salt-induced cardiac remodelling. 22291909

2012