Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 85458
Gene Symbol: DIXDC1
DIXDC1
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker CTD_human DIXDC1 contributes to psychiatric susceptibility by regulating dendritic spine and glutamatergic synapse density via GSK3 and Wnt/β-catenin signaling. 27752079

2018

Entrez Id: 7038
Gene Symbol: TG
TG
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker CTD_human Hashimoto's thyroiditis induces neuroinflammation and emotional alterations in euthyroid mice. 30373627

2018

Entrez Id: 135
Gene Symbol: ADORA2A
ADORA2A
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker CTD_human Caffeine Reverts Memory But Not Mood Impairment in a Depression-Prone Mouse Strain with Up-Regulated Adenosine A2A Receptor in Hippocampal Glutamate Synapses. 26860412

2017

Entrez Id: 6662
Gene Symbol: SOX9
SOX9
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker PSYGENET Differential co-expression and regulation analyses reveal different mechanisms underlying major depressive disorder and subsyndromal symptomatic depression. 25880836

2015

Entrez Id: 3131
Gene Symbol: HLF
HLF
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker PSYGENET Differential co-expression and regulation analyses reveal different mechanisms underlying major depressive disorder and subsyndromal symptomatic depression. 25880836

2015

Entrez Id: 65059
Gene Symbol: RAPH1
RAPH1
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker PSYGENET Blood transcriptomic biomarkers in adult primary care patients with major depressive disorder undergoing cognitive behavioral therapy. 25226551

2014

Entrez Id: 6369
Gene Symbol: CCL24
CCL24
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker PSYGENET Putative transcriptomic biomarkers in the inflammatory cytokine pathway differentiate major depressive disorder patients from control subjects and bipolar disorder patients. 24618828

2014

Entrez Id: 55830
Gene Symbol: GLT8D1
GLT8D1
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker PSYGENET ITIH3 polymorphism may confer susceptibility to psychiatric disorders by altering the expression levels of GLT8D1. 24373612

2014

Entrez Id: 6403
Gene Symbol: SELP
SELP
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker CTD_human Platelet hyperactivity, neurobehavioral symptoms and depression among Indian women chronically exposed to low level of arsenic. 25451969

2014

Entrez Id: 7015
Gene Symbol: TERT
TERT
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker PSYGENET Shortened telomere length in white matter oligodendrocytes in major depression: potential role of oxidative stress. 24967945

2014

Entrez Id: 51284
Gene Symbol: TLR7
TLR7
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker PSYGENET Blood transcriptomic biomarkers in adult primary care patients with major depressive disorder undergoing cognitive behavioral therapy. 25226551

2014

Entrez Id: 6844
Gene Symbol: VAMP2
VAMP2
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker PSYGENET The endogenous and reactive depression subtypes revisited: integrative animal and human studies implicate multiple distinct molecular mechanisms underlying major depressive disorder. 24886127

2014

Entrez Id: 9695
Gene Symbol: EDEM1
EDEM1
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker PSYGENET Elevated systemic expression of ER stress related genes is associated with stress-related mental disorders in the Detroit Neighborhood Health Study. 24703171

2014

Entrez Id: 2475
Gene Symbol: MTOR
MTOR
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker PSYGENET Gene expression analysis of novel genes in the prefrontal cortex of major depressive disorder subjects. 23261523

2013

Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker PSYGENET We have also quantified the mRNA of six genes previously identified as markers of the biopsychological stress associated with major depression: FOS, DUSP1, OGG1, STMN1, p16(INK4a) and TERT. 23668904

2013

Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker PSYGENET The alteration of hypoxia inducible factor-1 (HIF-1) and its target genes in mood disorder patients. 23333658

2013

Entrez Id: 3939
Gene Symbol: LDHA
LDHA
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker PSYGENET The alteration of hypoxia inducible factor-1 (HIF-1) and its target genes in mood disorder patients. 23333658

2013

Entrez Id: 4317
Gene Symbol: MMP8
MMP8
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker PSYGENET Genome-wide pathway analysis in major depressive disorder. 23794217

2013

Entrez Id: 2028
Gene Symbol: ENPEP
ENPEP
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker PSYGENET Genome-wide pathway analysis in major depressive disorder. 23794217

2013

Entrez Id: 5209
Gene Symbol: PFKFB3
PFKFB3
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker PSYGENET The alteration of hypoxia inducible factor-1 (HIF-1) and its target genes in mood disorder patients. 23333658

2013

Entrez Id: 4745
Gene Symbol: NELL1
NELL1
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker PSYGENET Gene expression analysis of novel genes in the prefrontal cortex of major depressive disorder subjects. 23261523

2013

Entrez Id: 3589
Gene Symbol: IL11
IL11
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker PSYGENET DNA methylation in interleukin-11 predicts clinical response to antidepressants in GENDEP. 24002086

2013

Entrez Id: 290
Gene Symbol: ANPEP
ANPEP
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker PSYGENET Genome-wide pathway analysis in major depressive disorder. 23794217

2013

Entrez Id: 2782
Gene Symbol: GNB1
GNB1
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker CTD_human Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains. 22113448

2012

Entrez Id: 2739
Gene Symbol: GLO1
GLO1
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.300 Biomarker CTD_human Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains. 22113448

2012