×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
GeneticVariation
CLINVAR
Endometrial cancer in four sisters: report of a kindred with presumed cancer family syndrome.
8063241 1994
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
CausalMutation
CLINVAR
Germline mutations in a polycytosine repeat of the hMSH6 gene in Korean hereditary nonpolyposis colorectal cancer.
9929971 1999
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
CausalMutation
CLINVAR
Germ-line msh6 mutations in colorectal cancer families.
10537275 1999
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
GeneticVariation
CLINVAR
Familial endometrial cancer in female carriers of MSH6 germline mutations.
10508506 1999
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
GeneticVariation
CLINVAR
Germ-line msh6 mutations in colorectal cancer families.
10537275 1999
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
CausalMutation
CLINVAR
Prevalence of defective DNA mismatch repair and MSH6 mutation in an unselected series of endometrial cancers.
12732731 2003
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
CausalMutation
CLINVAR
MSH6 germline mutations are rare in colorectal cancer families.
14520694 2003
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
CausalMutation
CLINVAR
Mutation analysis of the MLH1, MSH2 and MSH6 genes in patients with double primary cancers of the colorectum and the endometrium: a population-based study in northern Sweden.
14961575 2004
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
GeneticVariation
CLINVAR
Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance.
15236168 2004
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
CausalMutation
CLINVAR
Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance.
15236168 2004
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
CausalMutation
CLINVAR
Two Swedish founder MSH6 mutations, one nonsense and one missense, conferring high cumulative risk of Lynch syndrome.
16283884 2005
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
CausalMutation
CLINVAR
Compound heterozygosity for two MSH6 mutations in a patient with early onset of HNPCC-associated cancers, but without hematological malignancy and brain tumor.
16418736 2006
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
GeneticVariation
CLINVAR
Identification and survival of carriers of mutations in DNA mismatch-repair genes in colon cancer.
16807412 2006
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
CausalMutation
CLINVAR
Patients with an unexplained microsatellite instable tumour have a low risk of familial cancer.
17453009 2007
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
GeneticVariation
CLINVAR
Patients with an unexplained microsatellite instable tumour have a low risk of familial cancer.
17453009 2007
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
CausalMutation
CLINVAR
No association between MUTYH and MSH6 germline mutations in 64 HNPCC patients.
18301448 2008
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
CausalMutation
CLINVAR
Mutation spectrum in HNPCC in the Israeli population.
18389388 2008
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
CausalMutation
CLINVAR
A high incidence of MSH6 mutations in Amsterdam criteria II-negative families tested in a diagnostic setting.
18625694 2008
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
GeneticVariation
CLINVAR
Feasibility of screening for Lynch syndrome among patients with colorectal cancer.
18809606 2008
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
GeneticVariation
CLINVAR
Germline MSH6 mutations are more prevalent in endometrial cancer patient cohorts than hereditary non polyposis colorectal cancer cohorts.
18269114 2008
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
CausalMutation
CLINVAR
Major contribution from recurrent alterations and MSH6 mutations in the Danish Lynch syndrome population.
18566915 2009
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
GeneticVariation
CLINVAR
Major contribution from recurrent alterations and MSH6 mutations in the Danish Lynch syndrome population.
18566915 2009
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
CausalMutation
CLINVAR
An Ashkenazi founder mutation in the MSH6 gene leading to HNPCC.
19851887 2010
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
GeneticVariation
CLINVAR
Risks of Lynch syndrome cancers for MSH6 mutation carriers.
20028993 2010
×
Entrez Id: 2956
Gene Symbol: MSH6
MSH6
COLORECTAL CANCER, HEREDITARY NONPOLYPOSIS, TYPE 5
0.700
CausalMutation
CLINVAR
MSH6 and PMS2 mutation positive Australian Lynch syndrome families: novel mutations, cancer risk and age of diagnosis of colorectal cancer.
20487569 2010