×
Entrez Id: 7157
Gene Symbol: TP53
TP53
ovarian neoplasm
0.700
CausalMutation
CLINVAR
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
ovarian neoplasm
0.700
GeneticVariation
CLINVAR
×
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
ovarian neoplasm
0.700
CausalMutation
CLINVAR
×
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
ovarian neoplasm
0.700
GeneticVariation
CLINVAR
×
Entrez Id: 4978
Gene Symbol: OPCML
OPCML
ovarian neoplasm
0.630
CausalMutation
CLINVAR
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
ovarian neoplasm
0.500
GeneticVariation
CLINVAR
Prospective enterprise-level molecular genotyping of a cohort of cancer patients.
25157968 2014
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
ovarian neoplasm
0.500
CausalMutation
CLINVAR
BRAF(L597) mutations in melanoma are associated with sensitivity to MEK inhibitors.
22798288 2012
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
ovarian neoplasm
0.500
CausalMutation
CLINVAR
Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial.
22608338 2012
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
ovarian neoplasm
0.500
CausalMutation
CLINVAR
Epidermal growth factor receptor blockers for the treatment of ovarian cancer.
21975775 2011
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
ovarian neoplasm
0.500
CausalMutation
CLINVAR
Improved survival with vemurafenib in melanoma with BRAF V600E mutation.
21639808 2011
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
ovarian neoplasm
0.500
CausalMutation
CLINVAR
Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer--shifting the paradigm.
21683865 2011
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
ovarian neoplasm
0.500
CausalMutation
CLINVAR
Inhibition of mutated, activated BRAF in metastatic melanoma.
20818844 2010
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
ovarian neoplasm
0.500
CausalMutation
CLINVAR
Profound growth inhibition and apoptosis were observed in CI-1040-treated cancer cells with mutations in either KRAS or BRAF in comparison with the ovarian cancer cells containing wild-type sequences.
19018267 2008
×
Entrez Id: 673
Gene Symbol: BRAF
BRAF
ovarian neoplasm
0.500
CausalMutation
CLINVAR
Mutations of the BRAF gene in human cancer.
12068308 2002
×
Entrez Id: 5892
Gene Symbol: RAD51D
RAD51D
ovarian neoplasm
0.500
GeneticVariation
CLINVAR
×
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
ovarian neoplasm
0.500
CausalMutation
CLINVAR
×
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
ovarian neoplasm
0.500
GeneticVariation
CLINVAR
×
Entrez Id: 5892
Gene Symbol: RAD51D
RAD51D
ovarian neoplasm
0.500
CausalMutation
CLINVAR
×
Entrez Id: 83990
Gene Symbol: BRIP1
BRIP1
ovarian neoplasm
0.490
CausalMutation
CLINVAR
BRIP1 loss-of-function mutations confer high risk for familial ovarian cancer, but not familial breast cancer.
29368626 2018
×
Entrez Id: 83990
Gene Symbol: BRIP1
BRIP1
ovarian neoplasm
0.490
GeneticVariation
CLINVAR
BRIP1 loss-of-function mutations confer high risk for familial ovarian cancer, but not familial breast cancer.
29368626 2018
×
Entrez Id: 83990
Gene Symbol: BRIP1
BRIP1
ovarian neoplasm
0.490
CausalMutation
CLINVAR
Multiple-gene panel analysis in a case series of 255 women with hereditary breast and ovarian cancer.
28423363 2017
×
Entrez Id: 83990
Gene Symbol: BRIP1
BRIP1
ovarian neoplasm
0.490
CausalMutation
CLINVAR
Multigene panels in Ashkenazi Jewish patients yield high rates of actionable mutations in multiple non-BRCA cancer-associated genes.
28495237 2017
×
Entrez Id: 83990
Gene Symbol: BRIP1
BRIP1
ovarian neoplasm
0.490
CausalMutation
CLINVAR
Panel Testing for Familial Breast Cancer: Calibrating the Tension Between Research and Clinical Care.
26786923 2016
×
Entrez Id: 83990
Gene Symbol: BRIP1
BRIP1
ovarian neoplasm
0.490
GeneticVariation
CLINVAR
Inherited Mutations in Women With Ovarian Carcinoma.
26720728 2016
×
Entrez Id: 83990
Gene Symbol: BRIP1
BRIP1
ovarian neoplasm
0.490
GeneticVariation
CLINVAR
Germline multi-gene hereditary cancer panel testing in an unselected endometrial cancer cohort.
27443514 2016