Source: BEFREE

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker BEFREE Erythropoietin (Epo) is widely used clinically to treat anemia associated with various clinical conditions including cancer. 21860424

2012

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker BEFREE Erythropoietin (EPO) is currently used in low-risk MDS, where it successfully corrects anemia in 50-70% of patients. 22596089

2012

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker BEFREE Erythropoietin (EPO) deficiency or inadequate EPO secretion in response to bleeding may result in profound or prolonged anaemia after cardiac surgery. 28150286

2017

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker BEFREE Erythropoietin (EPO) has been used to treat anemia of cancer patients, because it stimulates erythropoiesis. 28247960

2017

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker BEFREE Erythropoietin, iron loading or transfusions are used to decrease preoperative anemia, a predisposing factor for blood loss. 28338491

2017

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker BEFREE Erythropoietin (EPO) is a well-known hormone that is clinically used for the treatment of anemia. 28383559

2017

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 AlteredExpression BEFREE Erythropoietin (EPO), known primarily for its erythropoietic activity, is commonly used clinically to treat anemia of chronic kidney disease. 28629513

2017

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker BEFREE EPO has been widely used in the treatment of chronic renal failure, cancer, and chemotherapy-related anemia for three decades. 28629521

2017

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker BEFREE Erythropoietin (EPO) is a heavily glycosylated hormone whose recombinant forms are used for treatment of anaemia. 28706253

2017

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker BEFREE Erythropoietin Fc (EPO-Fc) fusion proteins are potential drug candidates that have been designed for the treatment of anemia in humans by stimulating erythrocyte production. 29198116

2018

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker BEFREE Epoetin beta pegol for treatment of anemia ameliorates deterioration of erythrocyte quality associated with chronic kidney disease. 29374477

2018

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker BEFREE Erythropoietin mimetic peptides and erythropoietin fusion proteins for treating anemia of chronic kidney disease. 29746307

2018

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker BEFREE Epoetin-α reduced RBC transfusions and increased the time-to-first-transfusion compared with placebo.Thus, epoetin-α significantly improved anemia outcomes in low-risk MDS. 29895954

2018

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker BEFREE Erythropoietin response to anaemia in heart failure. 30068234

2019

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker BEFREE Erythropoietin (EPO) deficiency and resistance to endogenous EPO is an important pathophysiological feature in anemia of chronic kidney disease (CKD). 30136086

2018

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker BEFREE Erythropoietin (Epo) is used for the treatment of cancer‑associated anaemia. 30483799

2019

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker BEFREE Erythropoietin is used in a few patients with anaemia to overcome functional iron deficiency, and blood transfusion is being restricted to refractory cases or acute life-threatening situations. 30544934

2018

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker BEFREE Erythropoietin (EPO), a hematopoietic growth factor, acts primarily to stimulate erythroid cell production, and is clinically used to treat anemia. 30656553

2019

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 AlteredExpression BEFREE Erythropoietin levels were inappropriately low in relation to the degree of anaemia, but, in contrast to low haemoglobin, not directly associated with joint damage progression. 30941747

2019

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker BEFREE Erythropoietin (EPO) is one of the most successful biopharmaceuticals in history and is used for treating anemia of different origins. 30964047

2019

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker BEFREE EPO is usually to treat anemia in CKD and also improved in cognitive function. 31447360

2019

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker BEFREE Erythropoietin was administered for recurrent AZT-induced anaemia. 31471363

2019

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 GeneticVariation BEFREE Erythropoietin stimulating agents (ESAs), which are the cornerstone therapy for anemia patients with chronic kidney disease and cancer, are associated with increased risks for cancer, cancer-related mortality, progression of disease, and thromboembolic events. 31596520

2019

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker BEFREE A long-acting erythropoietin fused with noncytolytic human Fc for the treatment of anemia. 22644842

2012

Entrez Id: 2056
Gene Symbol: EPO
EPO
CUI: C0002871
Disease: Anemia
Anemia
0.500 Biomarker BEFREE A retrospective open-label uncontrolled study of Epoetin zeta on the treatment of chemotherapy-induced anemia in solid tumors. 28078434

2017