|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
CausalMutation |
CLINVAR |
Functional, structural, and genetic evaluation of 20 CDKN2A germ line mutations identified in melanoma-prone families or patients.
|
19260062 |
2009 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
Functional, structural, and genetic evaluation of 20 CDKN2A germ line mutations identified in melanoma-prone families or patients.
|
19260062 |
2009 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
Germline mutations in CDKN2A are infrequent in female patients with melanoma and breast cancer.
|
19571771 |
2009 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
Role of key-regulator genes in melanoma susceptibility and pathogenesis among patients from South Italy.
|
19799798 |
2009 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
CausalMutation |
CLINVAR |
CDKN2A mutations and MC1R variants in Italian patients with single or multiple primary melanoma.
|
18983535 |
2008 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
Biomarker |
CLINGEN |
p15Ink4b is a critical tumour suppressor in the absence of p16Ink4a.
|
17713536 |
2007 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
CDKN2A germline mutations in individuals with cutaneous malignant melanoma.
|
17218939 |
2007 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
CausalMutation |
CLINVAR |
MELPREDICT: a logistic regression model to estimate CDKN2A carrier probability.
|
16169933 |
2006 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
Familial melanoma, pancreatic cancer and germline CDKN2A mutations.
|
15146471 |
2004 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
Germline splicing mutations of CDKN2A predispose to melanoma.
|
14508519 |
2003 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
A single Mediterranean, possibly Jewish, origin for the Val59Gly CDKN2A mutation in four melanoma-prone families.
|
12700603 |
2003 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
CDKN2A point mutations D153spl(c.457G>T) and IVS2+1G>T result in aberrant splice products affecting both p16INK4a and p14ARF.
|
12853981 |
2003 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
CausalMutation |
CLINVAR |
Geographical variation in the penetrance of CDKN2A mutations for melanoma.
|
12072543 |
2002 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
Phenotypic variation in eight extended CDKN2A germline mutation familial atypical multiple mole melanoma-pancreatic carcinoma-prone families: the familial atypical mole melanoma-pancreatic carcinoma syndrome.
|
11815963 |
2002 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
Biomarker |
CLINGEN |
Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice.
|
11544530 |
2001 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
CDKN2A and CDK4 mutation analysis in Italian melanoma-prone families: functional characterization of a novel CDKN2A germ line mutation.
|
11556834 |
2001 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
CausalMutation |
CLINVAR |
A single genetic origin for the G101W CDKN2A mutation in 20 melanoma-prone families.
|
10869234 |
2000 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
CausalMutation |
CLINVAR |
Functional reassessment of P16 variants using a transfection-based assay.
|
10389768 |
1999 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
CausalMutation |
CLINVAR |
Mutation of the CDKN2A 5' UTR creates an aberrant initiation codon and predisposes to melanoma.
|
9916806 |
1999 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
Novel germline p16(INK4) allele (Asp145Cys) in a family with multiple pancreatic carcinomas. Mutations in brief no. 148. Online.
|
10627132 |
1998 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
Prevalence of p16 and CDK4 germline mutations in 48 melanoma-prone families in France. The French Familial Melanoma Study Group.
|
9425228 |
1998 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
Biomarker |
CLINGEN |
Haplotype analysis of two recurrent CDKN2A mutations in 10 melanoma families: evidence for common founders and independent mutations.
|
9603434 |
1998 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
CDKN2A mutations in multiple primary melanomas.
|
9516223 |
1998 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
GeneticVariation |
CLINVAR |
CDKN2A germline mutations in U.K. patients with familial melanoma and multiple primary melanomas.
|
9699728 |
1998 |
|
| Entrez Id: |
1029 |
| Gene Symbol: |
CDKN2A |
CDKN2A
|
MELANOMA-PANCREATIC CANCER SYNDROME
|
0.600 |
CausalMutation |
CLINVAR |
Prevalence of germ-line mutations in p16, p19ARF, and CDK4 in familial melanoma: analysis of a clinic-based population.
|
8710906 |
1996 |