×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
Biomarker
BEFREE
Behavioral stress inhibited apoptosis and delayed prostate tumor involution both in phosphatase and tensin homolog -deficient (PTEN -deficient) prostate cancer xenografts treated with PI3K inhibitor and in prostate tumors of mice with prostate-restricted expression of c-MYC (Hi-Myc mice) subjected to androgen ablation therapy with bicalutamide.
23348742 2013
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
Biomarker
BEFREE
High intracellular ROS levels selectively sensitize cells displaying hyperactive Akt to ROS-induced cell death enabling a therapeutic strategy combining a ROS inducer and rapamycin in PTEN -deficient prostate tumors in mouse models.
29687779 2018
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
Biomarker
BEFREE
KLF5 loss enhances tumor angiogenesis by attenuating PI3K/AKT signaling and subsequent accumulation of HIF1α in PTEN deficient prostate tumors .
25896712 2015
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
GeneticVariation
BEFREE
Using the conditional PTEN deletion mouse model, we previously reported that survivin levels increase with prostate tumor growth.
23936028 2013
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
Biomarker
CTD_human
Integrative molecular concept modeling of prostate cancer progression.
17173048 2007
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
Biomarker
CTD_human
Dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced prostate carcinogenesis in CYP1A-humanized mice.
22581815 2012
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
Biomarker
CTD_human
PTEN and GSK3beta: key regulators of progression to androgen-independent prostate cancer.
16421604 2006
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
Biomarker
CTD_human
Cribriform and intraductal prostate cancer are associated with increased genomic instability and distinct genomic alterations.
29295717 2018
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
Biomarker
CTD_human
The long tail of oncogenic drivers in prostate cancer.
29610475 2018
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
Biomarker
CTD_human
Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer.
22610119 2012
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
Biomarker
CTD_human
The pace of prostatic intraepithelial neoplasia development is determined by the timing of Pten tumor suppressor gene excision.
19081794 2008
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
Biomarker
CTD_human
Resveratrol and prostate cancer: promising role for microRNAs.
21714127 2011
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
Biomarker
CTD_human
Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate.
19396168 2009
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
Biomarker
CTD_human
Frequent inactivation of PTEN/MMAC1 in primary prostate cancer.
9371490 1997
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
Biomarker
CTD_human
A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes.
28319090 2017
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
Biomarker
CTD_human
Regulation of phosphatase homologue of tensin protein expression by bone morphogenetic proteins in prostate epithelial cells.
21456062 2011
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
Biomarker
CTD_human
Resveratrol regulates the PTEN/AKT pathway through androgen receptor-dependent and -independent mechanisms in prostate cancer cell lines.
20729295 2010
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
Biomarker
CTD_human
An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer.
29335545 2018
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
Biomarker
CTD_human
Dietary resveratrol prevents development of high-grade prostatic intraepithelial neoplastic lesions: involvement of SIRT1/S6K axis.
23248098 2013
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
PosttranslationalModification
LHGDN
Determining risk of biochemical recurrence in prostate cancer by immunohistochemical detection of PTEN expression and Akt activation.
17606718 2007
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
Biomarker
LHGDN
The role of PTEN in prostate cancer cell tropism to the bone micro-environment.
17347137 2007
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
GeneticVariation
LHGDN
PTEN mutations do not cause nuclear beta-catenin accumulation in endometrial carcinomas.
15492994 2004
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
Biomarker
LHGDN
[Role of PTEN protein in multidrug resistance of prostate cancer cells].
18702307 2008
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
AlteredExpression
LHGDN
Insulin growth factor-binding protein 2 is a candidate biomarker for PTEN status and PI3K/Akt pathway activation in glioblastoma and prostate cancer.
17372210 2007
×
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
Prostatic Neoplasms
0.600
AlteredExpression
LHGDN
Pten inactivation and the emergence of androgen-independent prostate cancer.
17638861 2007