×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
As mantle cell lymphoma is characterized by cyclin D1 overexpression, we assessed for human homolog of MDM4 (HDM4) expression and its effect on p21 in mantle cell lymphoma .
20062013 2010
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
GeneticVariation
BEFREE
Blastoid variants of mantle cell lymphoma : frequent bcl-1 rearrangements at the major translocation cluster region and tetraploid chromosome clones.
9028966 1997
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
BEFREE
CCND2 rearrangements are the most frequent genetic events in cyclin D1 (-) mantle cell lymphoma .
23255553 2013
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
BEFREE
Coexistence of BCL1/CCND1 and CMYC aberrations in blastoid mantle cell lymphoma : a rare finding associated with very poor outcome.
15138714 2004
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
BEFREE
Colocalization of BCL1 and c-MYC probes was demonstrated in a patient with mantle cell lymphoma .
15370207 2004
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
Complex analysis of cyclin D1 expression in mantle cell lymphoma : two cyclin D1 -negative cases detected.
19783727 2009
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
BEFREE
Concurrent disruption of cell cycle associated genes in mantle cell lymphoma : a genotypic and phenotypic study of cyclin D1 , p16, p15, p53 and pRb.
9697882 1998
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
Correlation of cyclin D1 transcript levels, transcript type and protein expression with proliferation and histology among mantle cell lymphoma .
18552173 2008
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
LHGDN
Cyclin Dl expression in B-cell non Hodgkin lymphoma.
17607588 2006
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
Detection of cyclin D1 overexpression by real-time reverse-transcriptase-mediated quantitative polymerase chain reaction for the diagnosis of mantle cell lymphoma .
11485900 2001
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
GeneticVariation
BEFREE
Detection of bcl-1 gene rearrangement and B-cell clonality in mantle cell lymphoma using formalin-fixed, paraffin-embedded tissues.
8526214 1995
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
GeneticVariation
BEFREE
Detection of t(12;14)(p13;q32) in a patient with IGH-CCND1 negative mantle cell lymphoma resembling ultra-high risk chronic lymphocytic leukemia.
26261659 2015
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
GeneticVariation
BEFREE
Detection of the bcl-1 rearrangement at the major translocation cluster in frozen and paraffin-embedded tissues of mantle cell lymphomas by polymerase chain reaction.
8623758 1996
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
BEFREE
Discovery and characterization of a novel CCND1 /MRCK gene fusion in mantle cell lymphoma .
27025456 2016
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
CTD_human
Dual inhibition of CDK4/Rb and PI3K/AKT/mTOR pathways by ON123300 induces synthetic lethality in mantle cell lymphomas.
26174628 2016
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
GeneticVariation
BEFREE
Dysregulation of cyclin D1 by a t(11;14)(q13;q32) translocation occurs in most cases of mantle-cell lymphoma and in approximately 30% of multiple myeloma (MM) tumors in which a 14q32 translocation can be detected.
8695815 1996
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
Elevated levels of expression of cyclin D1 protein have been found in a variety of cancers, including breast cancer, head and neck cancer, non-small-cell lung cancer, and mantle cell lymphomas .
8797766 1996
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
Expression of cyclin D1 protein in centrocytic/mantle cell lymphomas with and without rearrangement of the BCL1/cyclin D1 gene.
7545645 1995
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
Expression of retinoblastoma gene product (pRb) in mantle cell lymphomas . Correlation with cyclin D1 (PRAD1 /CCND1 ) mRNA levels and proliferative activity.
8623927 1996
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
Expression profiling of mantle cell lymphoma revealed that predominance of the 3'UTR-deficient, short cyclin D1 mRNA isoform was associated with high cyclin D1 levels, a high "proliferation signature" and poor prognosis.
22315488 2012
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
BEFREE
Flipping the cyclin D1 switch in mantle cell lymphoma .
22687450 2012
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
GeneticVariation
BEFREE
Fluorescence melting curve analysis for the detection of the bcl-1 /JH translocation in mantle cell lymphoma .
10092070 1999
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma .
12970790 2003
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
AlteredExpression
BEFREE
However, BCL1 expression from translocated allele with immunoglobulin gene is not down-regulated at the mantle zone stage, preventing cells from entering in resting state, and puts cells in cell cycle, leading to development of mantle cell lymphoma .
12430874 2002
×
Entrez Id: 595
Gene Symbol: CCND1
CCND1
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse
0.400
Biomarker
BEFREE
Identification of CD5/Cyclin D1 Double-negative Pleomorphic Mantle Cell Lymphoma : A Clinicopathologic, Genetic, and Gene Expression Study.
31688139 2020