×
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2
Liver Cirrhosis
0.570
Therapeutic
CTD_human
Nuclear erythroid 2-related factor 2: a novel potential therapeutic target for liver fibrosis.
23793039 2013
×
Entrez Id: 183
Gene Symbol: AGT
AGT
Liver Cirrhosis
0.560
Biomarker
CTD_human
Inhibition of cGMP-specific phosphodiesterase type 5 reduces sodium excretion and arterial blood pressure in patients with NaCl retention and ascites.
15613622 2005
×
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
Liver Cirrhosis
0.510
Biomarker
CTD_human
Gene Expression Patterns Associated With Histopathology in Toxic Liver Fibrosis.
26396155 2016
×
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
Liver Cirrhosis
0.510
Biomarker
CTD_human
Interleukin-6 protects hepatocytes from CCl4-mediated necrosis and apoptosis in mice by reducing MMP-2 expression.
15763341 2005
×
Entrez Id: 2321
Gene Symbol: FLT1
FLT1
Liver Cirrhosis
0.510
Biomarker
CTD_human
Hypoxia-induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis.
11981751 2002
×
Entrez Id: 2200
Gene Symbol: FBN1
FBN1
Liver Cirrhosis
0.500
Biomarker
CTD_human
Gene Expression Patterns Associated With Histopathology in Toxic Liver Fibrosis.
26396155 2016
×
Entrez Id: 210
Gene Symbol: ALAD
ALAD
Liver Cirrhosis
0.500
Biomarker
CTD_human
Characterization of chemically induced liver injuries using gene co-expression modules.
25226513 2014
×
Entrez Id: 540
Gene Symbol: ATP7B
ATP7B
Liver Cirrhosis
0.410
Biomarker
CTD_human
Wilson disease (WD) is caused by accumulation of excess copper (Cu) due to a mutation in the gene encoding the liver Cu transporter ATP7B , and is characterized by acute liver failure or cirrhosis and neuronal cell death.
25134866 2014
LGALS3BP
Liver Cirrhosis
0.400
Biomarker
CTD_human
Gene Expression Patterns Associated With Histopathology in Toxic Liver Fibrosis.
26396155 2016
SERPINA1
Liver Cirrhosis
0.400
Biomarker
CTD_human
AAT deficiency is a genetic disease that manifests with emphysema and liver cirrhosis due to the accumulation of a misfolded AAT mutant in hepatocytes.
25579632 2015
×
Entrez Id: 213
Gene Symbol: ALB
ALB
Liver Cirrhosis
0.400
Biomarker
CTD_human
This study aimed to assess IMA and IMAR as a liver function test and to investigate whether albumin infusion changes IMAR in patients with liver cirrhosis .
21851314 2011
SERPINA1
Liver Cirrhosis
0.400
Biomarker
CTD_human
Rapamycin reduces intrahepatic alpha-1-antitrypsin mutant Z protein polymers and liver injury in a mouse model.
20511674 2010
×
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
Liver Cirrhosis
0.400
Biomarker
CTD_human
The coagulation system contributes to alphaVbeta6 integrin expression and liver fibrosis induced by cholestasis.
21037076 2010
×
Entrez Id: 3439
Gene Symbol: IFNA1
IFNA1
Liver Cirrhosis
0.400
Therapeutic
CTD_human
These results suggest that IFN-alpha gene therapy is a promising strategy to treat HCC patients who have concomitant liver cirrhosis .
18665156 2008
×
Entrez Id: 213
Gene Symbol: ALB
ALB
Liver Cirrhosis
0.400
Biomarker
CTD_human
[Apolipoprotein A in patients with alcoholic liver disease].
17977396 2008
×
Entrez Id: 3082
Gene Symbol: HGF
HGF
Liver Cirrhosis
0.400
Therapeutic
CTD_human
Effects of hepatotrophic factors on the liver after portacaval shunt in rats with portal hypertension.
17097021 2006
×
Entrez Id: 5972
Gene Symbol: REN
REN
Liver Cirrhosis
0.400
Biomarker
CTD_human
In patients with ascites and cirrhosis , inhibition of PDE5 did not promote natriuresis but led to increased plasma levels of the renin -angiotensin-aldosterone system.
15613622 2005
×
Entrez Id: 3569
Gene Symbol: IL6
IL6
Liver Cirrhosis
0.400
Biomarker
CTD_human
Interleukin 6/gp130-dependent pathways are protective during chronic liver diseases.
12830005 2003
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Liver Cirrhosis
0.400
Biomarker
CTD_human
Hypoxia-induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis.
11981751 2002
×
Entrez Id: 2147
Gene Symbol: F2
F2
Liver Cirrhosis
0.400
Biomarker
CTD_human
Vitamin E reduces monocyte tissue factor expression in cirrhotic patients.
10216089 1999
SERPINA1
Liver Cirrhosis
0.400
Biomarker
CTD_human
We conclude that men with alpha 1-antitrypsin deficiency may be at higher risk for cirrhosis and primary liver cancer.
3485248 1986
×
Entrez Id: 929
Gene Symbol: CD14
CD14
Liver Cirrhosis
0.390
Biomarker
CTD_human
Elevated endotoxin levels in non-alcoholic fatty liver disease.
20353583 2010
×
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
Liver Cirrhosis
0.380
Biomarker
CTD_human
Tumor formation in liver of conditional β-catenin-deficient mice exposed to a diethylnitrosamine/phenobarbital tumor promotion regimen.
21047994 2011
×
Entrez Id: 5244
Gene Symbol: ABCB4
ABCB4
Liver Cirrhosis
0.360
Biomarker
CTD_human
Integrin beta6 mRNA increased with fibrosis stage in hepatitis C and was upregulated between 25- and 100-fold in TAA- and BDL-induced cirrhosis , in Mdr2 (Abcb4 )(-/-) mice and in human end-stage liver disease. alphavbeta6 protein was absent in normal livers and expressed de novo on (activated) bile duct epithelia and transitional hepatocytes.
18221819 2008
×
Entrez Id: 5244
Gene Symbol: ABCB4
ABCB4
Liver Cirrhosis
0.360
Biomarker
CTD_human
Effects of Ursodeoxycholate and cholate feeding on liver disease in FVB mice with a disrupted mdr2 P-glycoprotein gene.
8698195 1996